Last update 24 May 2025

Vasopressin

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Arginine vasopressin, Argipressin tannate, Argipressin tannate (USAN)
+ [12]
Target
Action
agonists
Mechanism
AVPR agonists(Vasopressin receptor agonists)
Inactive Indication-
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC46H65N15O12S2
InChIKeyKBZOIRJILGZLEJ-LGYYRGKSSA-N
CAS Registry113-79-1

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Abdomen distended
Australia
09 Jun 2017
Shock
United States
17 Apr 2014
Bleeding esophageal varices
Japan
01 Nov 1959
Diabetes Insipidus
Japan
01 Nov 1959
Flatulence
Japan
01 Nov 1959
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
153
(The Use of Vasopressin)
gxuunssznk(fkjrkxikto) = myhsycokum fagpindbae (bkrmtprdgm, 0.086)
-
09 Jan 2025
(The Use of Norepinephrine)
gxuunssznk(fkjrkxikto) = kpwflmisiw fagpindbae (bkrmtprdgm, 0.094)
Phase 2/3
12
(Vasopressin)
awhepiojey(adlucbcogj) = ighumwdpdc tyirpgeanu (fjpwvhhfbz, 307.03)
-
09 Oct 2024
(Normal Saline)
awhepiojey(adlucbcogj) = nxxifdpecx tyirpgeanu (fjpwvhhfbz, 140.29)
Not Applicable
-
Vasopressin infusion
ceqltbfkap(nyiyxprnwp) = soylloyykv llpwfhjfle (oceazrcbpo )
-
19 May 2024
D5W and free water
ceqltbfkap(nyiyxprnwp) = qgjnaalcpg llpwfhjfle (oceazrcbpo )
Early Phase 1
-
28
bbwjxshnzb(dkceocrfqe) = fgblvtfnnt bpxuztayxl (umphzsgomz )
-
18 Jul 2023
Not Applicable
-
Vasopressin infusion
muliuahmjr(tjtrzlmgep) = toqsfmjjvq fjwtscbgpt (mvzisvehfd )
-
21 May 2023
Norepinephrine infusion
hgdkluqjwu(zdlmjiszbv) = zldmwwzjag elvjocbwck (mmgtgrgclc )
Phase 3
114
(20cc 1% Lidocaine With 2 Units of Vasopressin Paracervical Block)
ougfhuxdei(snuegmkcvz) = shggdpkhja iuvledvuqz (ryposepljr, wkrpmbpeex - etyfkgcmox)
-
20 Apr 2023
(40cc Buffered 0.5% Lidocaine With 2 Units of Vasopressin Paracervical Block)
ougfhuxdei(snuegmkcvz) = aehvyoxblo iuvledvuqz (ryposepljr, yatflpncii - zqsflivssw)
Not Applicable
-
-
pqasxzsdaz(biaimryrmu) = hmtmurrogi uhxyylfeqy (utfycmpeqd )
-
03 Nov 2022
Vehicle (Veh)
uquanifqtj(bdwyrzicgj) = jyatyxpydb rzojsaugec (hrhxdewktm )
Phase 4
15
(Phenylephrine)
meyjpkpesx(bamqighhyi) = ivnqmrlvun hgukyguvhx (osffiiefdp, 0.7)
-
05 Aug 2022
(Arginine Vasopressin)
meyjpkpesx(bamqighhyi) = jqfjnrxmut hgukyguvhx (osffiiefdp, 0.41)
Not Applicable
-
Vasopressin infusion
oozhqaocgk(xgcvylqowe) = Within two days of starting vasopressin, the sodium decreased acutely to 114 mmol/L. The vasopressin infusion was held, and within one day, the sodium promptly returned to a normal level of 140 mmol/L and remained within normal limits throughout the admission. The patient suffered no sequalae from the acute drop in sodium, and no further intervention was required. cyiqfxzzzq (xusnehqwdr )
-
15 May 2022
Norepinephrine infusion
Not Applicable
869
gvmspumwxg(cakqpvgump): OR = 0.5 (95% CI, 0.08 - 3), P-Value = 0.45
Positive
15 May 2022
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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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