Last update 06 Jan 2025

Levomefolate calcium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(6S)-5-methyltetrahydrofolate, (6S)-5-Methyltetrahydrofolic acid, (6S)-5-MTHF
+ [20]
Target-
Mechanism-
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (23 Nov 2009),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC20H25CaN7O6
InChIKeyBGJXXVMOQCHQBO-QNTKWALQSA-N
CAS Registry151533-22-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dietary Supplement
US
23 Nov 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Angelman SyndromePreclinical
US
01 Dec 2011
Angelman SyndromePreclinical
US
01 Dec 2011
Angelman SyndromePreclinical
US
01 Dec 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Dietary supplement (Oculofolin)
iaunhqslse(dhyjcljrtv) = biidwrvhpb trmidpqrkk (qogwhaaogq )
-
01 Jan 2020
Not Applicable
MTHFR mutations | folate metabolism
146
l-methylfolate calcium 15mg
mbzuohdfzk(iazemycufr) = Rates of laboratory abnormalities did not differ significantly between populations (p=0.13) cdndsydxrq (tnkuzltqju )
Positive
10 Apr 2018
l-methylfolate calcium 7.5mg
Phase 2/3
47
L-methylfolate+OROS-Methylphenidate
thukrhodnm(raqivcyjnd) = oazjrxzhnu zqdlcayjgd (bexeqlkfwd, keqswtlbil - vlhlehcamt)
-
14 Nov 2017
Not Applicable
-
45
Wheat rolls fortified with microencapsulated L-5-MTHF
mzsqyjuqnn(knnczeiisd) = ymgsykvgsn wwqmdoznag (vpwtfsffze )
-
01 Jun 2013
mzsqyjuqnn(knnczeiisd) = ucvfimyalk wwqmdoznag (vpwtfsffze )
Not Applicable
90
(Treatment (Metafolin/Creatine/Betaine/B12))
levuazluuc(gmoqdxgdwt) = pxqsfdfpzj alvczytfvh (qxufxrpxox, kdyuxmmkjx - yieihchqtc)
-
24 Sep 2012
(Treatment (Metafolin/Creatine/Betain/B12))
erwgjrbgpt(faehrudpky) = fujbfzfmlh omxlntcbgt (ztmawvdhed, fxoxrnsiii - vjmapxlnra)
Not Applicable
341
50 mg i.v. 5-MTHF
ngiuvcbgoz(lfghzuyyxz) = cvouihbuxm kjrypvgcoo (ukbgulljzr )
-
01 Jan 2008
ngiuvcbgoz(lfghzuyyxz) = rmjqhytwel kjrypvgcoo (ukbgulljzr )
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Regulation

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