Recent blog posts
Medications intervening from the root of difficult and complex diseases: Oligonucleotides
Advanced Tech.
7 min read
Medications intervening from the root of difficult and complex diseases: Oligonucleotides
21 September 2023
Oligonucleotides (ONs) are a class of drugs composed of single or double strands of oligonucleotides synthesized by artificial chemistry.
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Important Research Area in Life Science: Growth Factors
Advanced Tech.
7 min read
Important Research Area in Life Science: Growth Factors
21 September 2023
Growth factors represent a class of polypeptides that regulate cell growth and various other cellular functions through binding with specific, high-affinity cell membrane receptors.
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An effective method to ward off viral intrusions: Toxoid Vaccine
Advanced Tech.
5 min read
An effective method to ward off viral intrusions: Toxoid Vaccine
20 September 2023
Toxoid Vaccine is essentially a bacterial toxin that is rendered harmless due to processing.
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"Super drugs" for treating cancer and AIDS: Chemokines family
Advanced Tech.
10 min read
"Super drugs" for treating cancer and AIDS: Chemokines family
19 September 2023
Chemokines, also known as chemotactic cytokines, are a group of factors that, in conjunction with their cell surface receptors, induce the directed migration of leukocytes.
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A type of emerging tumor treatment drug: Aptamers
Advanced Tech.
7 min read
A type of emerging tumor treatment drug: Aptamers
19 September 2023
Aptamers are short nucleotide sequences, typically DNA or RNA of 20 to 100 nucleotides.
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Important anti-cancer drug for tackling tumors: saRNA drug
Advanced Tech.
7 min read
Important anti-cancer drug for tackling tumors: saRNA drug
18 September 2023
Due to the small molecular weight and gene specificity of saRNA, it can be used to enhance the expression of specific proteins (products of tumor suppressor gene or haploinsufficient genes).
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Wang Shaomeng's research group reports AR receptor PROTAC drug ARD-1676, with a bioavailability as high as 99%
Advanced Tech.
9 min read
Wang Shaomeng's research group reports AR receptor PROTAC drug ARD-1676, with a bioavailability as high as 99%
14 September 2023
The research group of Wang Shaomeng recently published a paper in JMC, reporting the discovery of ARD-1676 and characterizing its preclinical properties.
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Inventory of Relay Pipeline and Eli Lilly's Acquisition of Kv1.3 Blockers
Advanced Tech.
8 min read
Inventory of Relay Pipeline and Eli Lilly's Acquisition of Kv1.3 Blockers
6 September 2023
Relay Therapeutics is a well-known drug discovery company in recent years, characterized by computational chemistry, with three drugs in its pipeline all from D.E. Shaw.
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The Mechanism of Interferons Antiviral Action and Its Biological Activity
Advanced Tech.
5 min read
The Mechanism of Interferons Antiviral Action and Its Biological Activity
2 September 2023
Interferon (IFN) is a type of crucial cytokine, capable of directly participating in the antiviral immune response of epithelial cells, mediating the natural immune response to induce the expression of Interferon Stimulated Genes (ISG), hence, swiftly establishing the body's natural immune defense line against viral infections.
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Exosomes and Tumor Immunotherapy
Advanced Tech.
6 min read
Exosomes and Tumor Immunotherapy
30 August 2023
Research on tumor immune evasion and tolerance mediated by exosomes has found that tumor cells can produce a large amount of exosomes.
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Can Arvinas lead the treatment of neurodegenerative diseases?
Advanced Tech.
8 min read
Can Arvinas lead the treatment of neurodegenerative diseases?
25 August 2023
Arvinas is currently conducting preclinical studies on protein degradation for neurodegenerative diseases.
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Zoledronic Acid holds the key in Fighting Aging-Related Diseases
Advanced Tech.
6 min read
Zoledronic Acid holds the key in Fighting Aging-Related Diseases
22 August 2023
A recent study published in journal Aging has shed light on the potential anti-aging effects of zoledronic acid, a commonly prescribed bisphosphonate.
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