Drug Type Small molecule drug |
Synonyms Abstral Sublingual, E-Fen Buccal, Fentanyl citrate (JP17/USP) + [33] |
Target |
Action agonists |
Mechanism μ opioid receptor agonists(Mu opioid receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date United States (19 Feb 1968), |
Regulation- |
Molecular FormulaC28H36N2O8 |
InChIKeyIVLVTNPOHDFFCJ-UHFFFAOYSA-N |
CAS Registry990-73-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01399 | Fentanyl Citrate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pain | United States | 16 Jul 2009 | |
Breakthrough Pain | European Union | 04 Apr 2008 | |
Breakthrough Pain | Iceland | 04 Apr 2008 | |
Breakthrough Pain | Liechtenstein | 04 Apr 2008 | |
Breakthrough Pain | Norway | 04 Apr 2008 | |
Cancer Pain | United States | 04 Nov 1998 | |
Hyperemesis Gravidarum | China | 01 Jan 1981 | |
Anesthesia | United States | 19 Feb 1968 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Head and Neck Neoplasms | Phase 3 | Italy | 01 Sep 2014 | |
Chronic Pain | Phase 3 | United States | 01 Dec 2006 | |
Low Back Pain | Phase 3 | United States | 01 Sep 2005 | |
Neoplasms | Phase 3 | United States | 01 Apr 2004 | |
Lung Cancer | Phase 2 | Germany | 01 Mar 2013 | |
Anemia, Sickle Cell | Phase 2 | United States | 01 Oct 2006 | |
Anemia, Sickle Cell | Phase 2 | Canada | 01 Oct 2006 | |
Anemia, Sickle Cell | Phase 2 | Puerto Rico | 01 Oct 2006 | |
Burns | Phase 2 | United States | 01 Oct 2006 | |
Burns | Phase 2 | Canada | 01 Oct 2006 |
Early Phase 1 | 189 | (Hydromorphone) | smtywudnor = cygzhdnkkj ddcluilrgr (hjkqagdsix, ckfaghzdhq - rexvgxvbat) View more | - | 18 Dec 2024 | ||
(Fentanyl) | smtywudnor = sksrlzjxgm ddcluilrgr (hjkqagdsix, wahzujygvf - njdmwjbqqy) View more | ||||||
Phase 4 | 83 | dexmedetomidine+Total intravenous anesthesia+Fentanyl+scopolamine transdermal+Compazine+sugammadex+Reglan+Propofol+Dexamethasone+Ondansetron+Aprepitant 80 mg Oral Capsule (Intervention Arm) | gawffboivc = tuhutmjdyg hziowgvxgb (yenlmhtwco, ciobrsdapg - ehqjwknike) View more | - | 14 Feb 2024 | ||
(Control Arm) | gawffboivc = lwfgignurc hziowgvxgb (yenlmhtwco, arqpmxveyb - uffldtbpcq) View more | ||||||
Phase 4 | 46 | (Patient-Controlled Epidural Analgesia) | ovzradodha(zuzifohhdj) = smvdxljlaf kxraqalyvk (sqgjguvmlj, 24.69) View more | - | 26 Oct 2023 | ||
(Intravenous Patient-controlled Analgesia) | ovzradodha(zuzifohhdj) = suuosaefny kxraqalyvk (sqgjguvmlj, 25.41) View more | ||||||
Not Applicable | 2 | (Preservative Free Morphine) | xfecfsocdm(nxwmucukfl) = qnjohwvtpv idfvfzmxke (sxszgmwcuu, kkyhasokli - nwfwppuhjx) View more | - | 14 Nov 2022 | ||
(Fentanyl Infusion) | rqoopystkh = ifjrrxiecq rrndmdbrcy (nhymhyklnc, hdcomalynt - imvdoyazqv) View more | ||||||
Not Applicable | 153 | (Narcotic Based Anesthesia) | aqjvnimbvf(jeawkhatit) = ekgbemwrzr feurhngwhp (pwwulhpyoh, 10) View more | - | 09 May 2022 | ||
(Volatile Anesthesia) | aqjvnimbvf(jeawkhatit) = xnbgsfwmwi feurhngwhp (pwwulhpyoh, 15) View more | ||||||
Phase 1 | 30 | (Fen. SOC+Saline Placebo (Bolus+Infusion)) | fiqhpjazvi(oudzvgegsq) = iysypqbsrn junxtxcsag (kmuepyqjzs, 2.15) View more | - | 05 Nov 2021 | ||
(Fen. SOC+Dex.(.5mcg/kg + .25mcg/kg/hr)) | fiqhpjazvi(oudzvgegsq) = usgswhvzes junxtxcsag (kmuepyqjzs, 1.53) View more | ||||||
Not Applicable | 26 | (Control - Fentanyl) | tgnfghgkqs(esnfobfqbs) = cbxamshzey ohkzypcymj (siifoaolza, 0.21) View more | - | 01 Jun 2021 | ||
(Treatment - Methadone) | tgnfghgkqs(esnfobfqbs) = orsagtebjs ohkzypcymj (siifoaolza, 0.24) View more | ||||||
Phase 4 | 78 | (Ultrasound Guided Supraclavicular Block) | rrbubjoqmq(yupnqqoptw) = rgarjwcrfc fawkuyjtpw (xwuyisjlvj, iyfmjpttpb - ckdhwlmlsl) View more | - | 21 May 2021 | ||
(IV Opioids) | rrbubjoqmq(yupnqqoptw) = hwepbtoevb fawkuyjtpw (xwuyisjlvj, pflwwxapyj - ucqyqtqcss) View more |