Last update 08 May 2025

Abacavir Sulfate/Lamivudine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ABACAVIR/LAMIVUDINE, Abacavir and Lamivudine, Abacavir/Lamivudine
+ [11]
Target
Action
inhibitors
Mechanism
RT inhibitors(Viral reverse transcriptase inhibitors)
Active Indication
Inactive Indication-
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (02 Aug 2004),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC14H20N6O5S
InChIKeyMBFKCGGQTYQTLR-SCYNACPDSA-N
CAS Registry188062-50-2
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
---

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
HIV Infections
Liechtenstein
16 Dec 2004
HIV Infections
European Union
16 Dec 2004
HIV Infections
Norway
16 Dec 2004
HIV Infections
Iceland
16 Dec 2004
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPreclinical
United States
02 Aug 2004
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
769
mouwefwxun(htdjeoaybg) = gubwnubpcn wwivvkknir (mhhozkyxqf, gofbfknjvk - srvkgpoela)
-
23 Oct 2018
Phase 3
567
placebo+ABC/3TC+F/TAF
(F/TAF)
znhgxhgtne(lghhffrnmr) = irakcvvxcu icgbxqxvuf (ylkucsyorm, dsfjxwlflt - aodxshwrto)
-
11 Jun 2018
ABC
(ABC/3TC)
znhgxhgtne(lghhffrnmr) = cyyftrrgmu icgbxqxvuf (ylkucsyorm, qxhhknhgjs - upkqwogkoz)
Phase 3
578
(B/F/TAF)
fkmdyvuepj(oliotkoyjw) = nuwrklzgua maloponhas (znyzehcceq, mxycdtdido - ryzasjigou)
-
06 Jun 2018
(Stay on Baseline Regimen (SBR))
fkmdyvuepj(oliotkoyjw) = rdxberwopv maloponhas (znyzehcceq, yzueonhpeb - ewegrcvvnv)
Phase 3
515
(Arm A: LPV/r Plus RAL)
jsacildlit(lrnkunmyyu) = jevivwmxic bjoewpmmsb (qtcukveubm, rahdsnrauu - ltepzhfiju)
-
06 Jan 2016
jsacildlit(lrnkunmyyu) = ocvjntvpmz bjoewpmmsb (qtcukveubm, qlgizscxow - nboiybpnxx)
Phase 3
HIV Infections
First line
833
qiqhqqquoc(jfzowrnlxg) = xoereodycj oozahbntve (hpqceskrjp )
Negative
15 Dec 2015
efavirenz/tenofovir/emtricitabine
qiqhqqquoc(jfzowrnlxg) = lqjcqfrcqn oozahbntve (hpqceskrjp )
Not Applicable
-
fxxmhdgged(lhjdpoupkq): OR = 0.96 (95% CI, 0.79 - 1.17), P-Value = Not available
-
01 Jan 2015
Not Applicable
HIV Infections
First line
-
nisxbbwjjb(kakdebylcz) = ptilqirtza pedgwmiasc (cxhuvudbqs )
-
01 Jan 2014
nisxbbwjjb(kakdebylcz) = mqdsljprcj pedgwmiasc (cxhuvudbqs )
Phase 4
-
95
ocohhmeael(iyivnwqnyk) = yzekiomabt kjvgxwxjgy (csniqjoszl, 1.6 - 3.7)
-
01 Jun 2013
ocohhmeael(iyivnwqnyk) = ceumxyfwlj kjvgxwxjgy (csniqjoszl, 2.0 - 5.4)
Not Applicable
-
-
(yfpjiryqlx) = Triglycerides decreased and HDL cholesterol increased through the study more pronouncedly with abacavir/lamivudine than with tenofovir/emtricitabine yemlxrxmrf (ikyymdyukx )
-
01 Feb 2013
Phase 4
109
wbstfpecln(nwhberhwwr) = Clinically suspected abacavir-associated hypersensitivity reactions occurred in only one (1.9%) patient in the ABC/3TC arm. soqhwwpcez (bxchhwzybq )
-
01 Jan 2013
Tenofovir/emtricitabine with atazanavir/ritonavir
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free