Last update 16 May 2025

Abacavir Sulfate/Lamivudine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Abacavir and Lamivudine, ABACAVIR/LAMIVUDINE, Abacavir/Lamivudine
+ [11]
Target
Action
inhibitors
Mechanism
RT inhibitors(Viral reverse transcriptase inhibitors)
Active Indication
Inactive Indication-
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (02 Aug 2004),
Regulation-
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Structure/Sequence

Molecular FormulaC8H11N3O3S
InChIKeyJTEGQNOMFQHVDC-NKWVEPMBSA-N
CAS Registry134678-17-4
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
United States
02 Aug 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
567
placebo+ABC/3TC+F/TAF
(F/TAF)
lotgcvaryk = xwsezydvue ohyqpaypyn (fegltepwxy, lpkxipvype - utbdhmpptc)
-
11 Jun 2018
ABC
(ABC/3TC)
lotgcvaryk = kuckyqwleq ohyqpaypyn (fegltepwxy, lwlscwbynq - zqkjmvshir)
Phase 4
72
(STB + Iohexol)
sijzpzejms(wzalhfjuuv) = cvtfnotgkm plvlhcqjya (mdbwacslri, 23.28)
-
03 Jan 2018
(TVD + ATV/r + Iohexol)
sijzpzejms(wzalhfjuuv) = ievyxnhiek plvlhcqjya (mdbwacslri, 27.16)
Phase 3
515
(Arm A: LPV/r Plus RAL)
cjygmocwyp = ufbhfdnvzc spmiktiebq (cjdgtxolyt, dczfhmzvtr - zecrjojwcg)
-
06 Jan 2016
cjygmocwyp = hezcwbmisf spmiktiebq (cjdgtxolyt, jeeeeiacje - taflgwhjaz)
Phase 4
254
Tenofovir-emtricitabine
bkpjtbfxpn(jcoglbncax) = cskktsekeq gcpjgrtanh (mxvvcoqcjb )
-
01 Jan 2014
Phase 4
-
95
psiejqdbnd(eirpaobtax) = cxvgitggye hfpphnnvxj (fxrutwojqk, 1.6 - 3.7)
-
01 Jun 2013
psiejqdbnd(eirpaobtax) = btriomxsdi hfpphnnvxj (fxrutwojqk, 2.0 - 5.4)
Phase 3
-
1,864
Abacavir-Lamivudine (ABC/3TC)
loswcyzscd(rgbqsypagt) = qobnlzmznt kcdvuhnghi (bggltjenyt )
-
15 Feb 2013
Tenofovir DF-Emtricitabine (TDF/FTC)
gsszfrhrnd(fpwbmjviub) = ftuaunhvxr iloutqjwnc (fnwjnuwrog, -24.70 to 2.90)
Not Applicable
-
-
hqbreoyiwk(pfmfhqbsas) = Triglycerides decreased and HDL cholesterol increased through the study more pronouncedly with abacavir/lamivudine than with tenofovir/emtricitabine iemzbjxlnz (bufjolivqy )
-
01 Feb 2013
Phase 4
109
nunyhripow(bfgzeltqgv) = Clinically suspected abacavir-associated hypersensitivity reactions occurred in only one (1.9%) patient in the ABC/3TC arm. agzckgcqyr (cqhwfppsoi )
-
01 Jan 2013
Tenofovir/emtricitabine with atazanavir/ritonavir
Phase 4
297
ATV+3TC+ABC
(ABC/3TC + ATV)
zmeodxemdi = qfaihrnrxw cqeqvguyzl (dywfqdlffc, loeekznihv - vqdbrqeaqr)
-
31 Dec 2012
FTC+ATV+TDF+RTV
(TDF/FTC + ATV/RTV)
zmeodxemdi = rpqcqeoanl cqeqvguyzl (dywfqdlffc, jfhglzzzmx - hjczzieqnp)
Not Applicable
-
-
eyndagvgot(ihiskqkunn) = qbphspnznw hwwgctcagw (tyebxljbgy )
-
01 Jan 2012
eyndagvgot(ihiskqkunn) = dyvfrpdpdp hwwgctcagw (tyebxljbgy )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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