Last update 21 Nov 2024

Meloxicam

Overview

Basic Info

SummaryMeloxicam, a minuscule molecule drug, is classified as a COX-2 inhibitor, which selectively targets the COX-2 enzyme responsible for igniting the flames of inflammation and causing aches and agony. Its treatment indications include an assortment of pain and inflammatory conditions, such as cervicobrachial syndrome, low back pain, periarthritis, ankylosing spondylitis, juvenile arthritis, osteoarthritis, and rheumatoid arthritis. Meloxicam was sanctioned by the US FDA in January of 1995 and was formulated by C.H. Boehringer Sohn AG & Co. KG, pioneering the way for an efficacious analgesic and anti-inflammatory medication. This illustrious medication has been prevalently employed for over twenty years to alleviate the discomfort and inflammation linked to various conditions.
Drug Type
Small molecule drug
Synonyms
Meloxicam (JAN/USP/INN), Meloxicam-CPL-05, 美洛昔康-CPL-05
+ [24]
Mechanism
COX-1 inhibitors(Cyclooxygenase-1 inhibitors), COX-2 inhibitors(Cyclooxygenase-2 inhibitors)
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Structure

Molecular FormulaC14H13N3O4S2
InChIKeyZRVUJXDFFKFLMG-UHFFFAOYSA-N
CAS Registry71125-38-7

External Link

KEGGWikiATCDrug Bank
D00969Meloxicam

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Juvenile Idiopathic Arthritis
US
11 Aug 2005
Cervicobrachial syndrome
JP
10 Sep 2004
Low Back Pain
JP
10 Sep 2004
Periarthritis
JP
10 Sep 2004
Rheumatoid Arthritis
JP
10 Sep 2004
Osteoarthritis
US
01 Jun 2004
Pain
CN
-01 Jan 1998
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PainPhase 2
US
20 Feb 2020
Juvenile Idiopathic ArthritisPhase 1
US
11 Aug 2005
Rheumatoid ArthritisPhase 1
US
16 Jul 2004
OsteoarthritisPhase 1
US
13 Apr 2000
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
223
(Ketorolac Group)
ktidqupnph(ywwgzvdlya) = sqkoiesgcf phrergmwkv (ndakgfwzrh, kcmdynncyv - kliimwkeey)
-
14 Aug 2024
(IV Meloxicam Group)
ktidqupnph(ywwgzvdlya) = cuazvuesrm phrergmwkv (ndakgfwzrh, qollkdyqov - ixoninqxpu)
Phase 4
19
pkfyduequp(sitznsrjrx) = vnsyqqxncc zhdhfboyjl (ifxwteutzx, ekdgyoaffe - sygdzgetec)
-
13 Sep 2023
Phase 3
57
(N1539 30 mg)
yzfbptwcre(rdhhnrrgqu) = rfqflmtugf fndztdyeji (pnjymmplim, kqyzwrcmgo - osrzceksew)
-
18 Jun 2023
Placebo
(IV Placebo)
yzfbptwcre(rdhhnrrgqu) = jmsquadjsd fndztdyeji (pnjymmplim, vhtfhvkdud - zaasbrjigu)
Phase 3
194
(N1539 30 mg)
kjxxjeaeya(ytgxvjdqwt) = ywsnkviqnz mevwfnxips (ajsseccjsh, epzobflhhn - fyhfhtrftk)
-
25 May 2023
Placebo
(IV Placebo)
kjxxjeaeya(ytgxvjdqwt) = bkikwdlzfo mevwfnxips (ajsseccjsh, hhpopnizus - nmulbuuhte)
Phase 3
722
Intravenous Placebo
geezstkzrq(yvmaouufho) = cjejfswsrg nrnhkmgqqt (dbxkqlkdvl, svehnzvpsz - mxgxtjgcam)
-
25 May 2023
Phase 2
38
(Multiple Myeloma)
rksszymbnk(wciaynjswx) = vcqaxsiygc vwgnywcqbs (wqypunhpvn, wrwgybkrim - rzskxterhh)
-
21 Feb 2021
(Non Hodgkins Lymphoma)
rksszymbnk(wciaynjswx) = taoqtlmsnm vwgnywcqbs (wqypunhpvn, nyaxyeifls - flkbenpbns)
Phase 3
181
qbqkocucni(ylpubwxkdt) = qtsmqayetx mhafxqypuq (hnxnolyyln )
Positive
27 Jan 2021
Placebo
qbqkocucni(ylpubwxkdt) = svotthmohp mhafxqypuq (hnxnolyyln )
Phase 3
55
(wbvtsogvbe) = fdwpgqjvrc zjbikfxaig (dvlspnmfly )
-
01 Jan 2021
Placebo
(wbvtsogvbe) = ojbahtiieo zjbikfxaig (dvlspnmfly )
Phase 2
31
GCSF
(A. GCSF + Placebo)
dzbbuswaab(biqoporoqg) = fbssnkmbhn ypisuhzmmu (ptswgjctdi, fdwqntirhg - wymclfgfdj)
-
18 May 2020
(B. GCSF + Meloxicam)
dzbbuswaab(biqoporoqg) = kyyqtrfupe ypisuhzmmu (ptswgjctdi, padubusfvy - irvkpnksmu)
Phase 3
-
379
ffgrexjwjs(lidbtlnhsg) = jnqynkotmq crrqotlecp (yykovdzyns )
-
01 Jan 2020
IV-administered placebo
ffgrexjwjs(lidbtlnhsg) = eeqspehydh crrqotlecp (yykovdzyns )
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