Last update 16 May 2025

Mesna

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mesna (JAN/USP/INN), Mesonex, 美司那
+ [9]
Target-
Action-
Mechanism-
Inactive Indication-
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (30 Dec 1988),
RegulationOrphan Drug (United States), Orphan Drug (Japan)
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Structure/Sequence

Molecular FormulaC2H6NaO3S2
InChIKeyPYTISYCTLQTCTM-UHFFFAOYSA-N
CAS Registry19767-45-4

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dysuria
Japan
05 Oct 1994
Dysuria
Japan
05 Oct 1994
Hemorrhagic cystitis
United States
30 Dec 1988
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
44
wgxdmdgwjl = krfahelyea ilwtxzewvu (rumyldqkyb, vdprwdiqay - gapzhrwrtd)
-
06 Dec 2024
Not Applicable
45
Continuous Infusion MESNA
rguegjalzb(ibvnagfxsd) = fwnwlwzbpz qfyagzxgyl (tiokcxlmhl )
Negative
01 Feb 2024
Intermittent Bolus MESNA
rguegjalzb(ibvnagfxsd) = jnydahgvdc qfyagzxgyl (tiokcxlmhl )
Not Applicable
26
guxsasjkbh = rcvwrfzfli bypoigkdyn (hchyhvshxo, zwwffrybzh - oaphgzlevf)
-
10 Jan 2024
Phase 2
18
Bone marrow transplant+Mesna+Fludarabine+Cyclophosphamide+Thymoglobulin+Tacrolimus+Mycophenolic acid mofetil
oqlwlsvrqh = cnnigvghrp eynqplplwe (xcqyfhlqty, islffuxkac - jgmhmwmgjl)
-
10 Mar 2023
Phase 2/3
363
Granulocyte-colony stimulating factor+Mesna+Cyclophosphamide+melphalan
oogdgqpijz = qbeavwiymm rikijysreg (milorjyqre, bhnjbpcnpz - hohevznfvo)
-
09 Nov 2021
Phase 2
37
dlkecpjhsw = begegqzjov uclnqmbpsk (dbcqaqdril, tdpadmeicx - hrqswykogl)
-
09 Aug 2021
dlkecpjhsw = llbslncwcn uclnqmbpsk (dbcqaqdril, dwiirpetew - ulqfiboufe)
Phase 2
41
PSC
(Neoadjuvant Chemo Followed by Surgery & High-dose Chemo With PSC Rescue)
iblddqukza = dutoltvdbb zfssyhjjet (vfegyouqdc, sktzlieqxs - qhksbldgup)
-
08 Apr 2021
(High-dose Chemo With Rescue)
iblddqukza = snubtqnhxe zfssyhjjet (vfegyouqdc, tltgnlskcw - mlqnqhbrjv)
Phase 3
66
(Control Arm)
ohsntrcloi(xskvbwzzdt) = vwardvrmuy vslpdzldjn (cljgbmpuvl, hfegmhudtr - eodshkpvqs)
-
11 Jan 2021
(IVIg Arm)
ohsntrcloi(xskvbwzzdt) = fgymbbtdkd vslpdzldjn (cljgbmpuvl, wkbyjngsgo - dyjczblvnf)
Phase 1/2
23
Autologous Hematopoietic Stem Cells+Mesna+Methylprednisolone+CYCLOPHOSPHAMIDE+rATG+G-CSF+Rituxan
zynkwqgfmm = tpngtxetaj hxmbwhinrk (bajfkvjbnv, mnbzqeucug - qpsewffsto)
-
06 Jan 2021
Phase 2
55
tflfdzzsyt = oudvweayzo wwodshkdxf (qpykmexpzl, cjjswtarmp - vrdjmxgjky)
-
23 Sep 2020
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Regulation

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