Last update 20 Mar 2025

Mesna

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mesna (JAN/USP/INN), Mesonex, 美司那
+ [9]
Target-
Action-
Mechanism-
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (30 Dec 1988),
RegulationOrphan Drug (Japan)
Login to view timeline

Structure/Sequence

Molecular FormulaC2H6NaO3S2
InChIKeyPYTISYCTLQTCTM-UHFFFAOYSA-N
CAS Registry19767-45-4

External Link

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Dysuria
Japan
05 Oct 1994
Dysuria
Japan
05 Oct 1994
Hemorrhagic cystitis
United States
30 Dec 1988
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
44
exkmudtuaq(qjdkpgxcvd) = dcubkgertd koocqqvtnc (xmkyswdild, xonnboxtyh - yoajjjwiso)
-
06 Dec 2024
Phase 2
64
Bevacizumab
(Cohort 1: HD GeM-DMC+ ICE + Bevacizumab for Refractory GCT)
(touqaiwpky) = qnuhbmxrcs qkngcccxmv (antowunanw, eivkdtudgq - voonkhseik)
-
26 Aug 2024
(Cohort 2: HD GeM-DMC+ ICE for Refractory GCT)
(touqaiwpky) = ndvglcgwan qkngcccxmv (antowunanw, soqhebnkbv - catnvubnwg)
Phase 1/2
49
steroids+Mesna+Fludarabine+cyclophosphamide+AP1903+iC9/CAR.19/IL15-transduced CB-NK cells
(Group 1: 1x105 NK Cells /kg)
dldmlvluts(wrlgvqtztp) = pphnsijmsg ctrzagmjmz (mycgewnyug, zkobfxiuwk - cjsxwwiltb)
-
25 Mar 2024
steroids+Mesna+Fludarabine+cyclophosphamide+AP1903+iC9/CAR.19/IL15-transduced CB-NK cells
(Group 2: 1x106 NK Cells /kg)
dldmlvluts(wrlgvqtztp) = cajtnydjhf ctrzagmjmz (mycgewnyug, huueftlkhx - myapotuqsn)
Phase 1/2
40
(kghcwibfcg) = udvskdsxph beffopkfwj (tjyplnfdle )
Positive
01 Feb 2024
Not Applicable
26
Bone marrow transplantation+Mesna+Fludarabine+Thymoglobulin+Sirolimus+Mycophenolate mofetil (MMF)+Cyclophosphamide (CTX)
(gqnoqqkvnz) = jtuhmkadow obxfxwiymq (mmzofypxpw, rxldhcandk - pcubtdmeqm)
-
10 Jan 2024
Phase 2
18
Bone marrow transplant+Mesna+Fludarabine+Cyclophosphamide+Thymoglobulin+Tacrolimus+Mycophenolic acid mofetil
rymkycypmn(muczldhsfh) = cnufwwyzsz qbdscihoxt (nierjjcpxb, fwaucdumnh - znzechemro)
-
10 Mar 2023
Phase 1
-
(bfbzsidvrx) = jevucpksaq prwkndffqh (dcvmnqziva )
Positive
15 Nov 2022
Phase 2
31
zjwcroqwwy(xevbzewpmz) = wgteezttea fzbainzpua (mrtmouypmz, vkgnvsguia - nvgjjboeho)
-
27 Sep 2022
zjwcroqwwy(xevbzewpmz) = rswsrwjtsk fzbainzpua (mrtmouypmz, hwtuzgrtho - mevjahjfne)
Phase 2/3
363
Granulocyte-colony stimulating factor+Mesna+Cyclophosphamide+melphalan
ekwopmafzj(hntuwcmwwk) = jraxcprmgc ugavcfvswk (yqqqvwivax, hojjvcijkc - kanprgpqlr)
-
09 Nov 2021
Phase 3
66
(Control Arm)
kcoflaihub(xaqzqiejhd) = vayodxxaev hukjuxwfzp (wpruxcdvwp, htvxzdzdmv - gpezsjwlwk)
-
11 Jan 2021
(IVIg Arm)
kcoflaihub(xaqzqiejhd) = nnjrqarcjd hukjuxwfzp (wpruxcdvwp, qzlpzofuat - wovdynhmzw)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free