Last update 08 May 2025

Lamivudine/Raltegravir Potassium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DUTREBIS, Lamivudine/raltegravir, Raltegravir/3TC
+ [3]
Action
inhibitors
Mechanism
HIV-1 integrase inhibitors(HIV integrase inhibitors), RT inhibitors(Viral reverse transcriptase inhibitors)
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhaseWithdrawn
First Approval Date
United States (06 Feb 2015),
Regulation-
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Structure/Sequence

Molecular FormulaC20H21FKN6O5
InChIKeyNLDVPINGTPMESH-UHFFFAOYSA-N
CAS Registry871038-72-1
View All Structures (2)

External Link

R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
phfcqasjno(pthcetuwwp) = hvuhdvkvrz hfnfnhvevi (eyqjrizrvc, (179))
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01 Jan 2020
phfcqasjno(pthcetuwwp) = boeyipevjg hfnfnhvevi (eyqjrizrvc, (449))
Not Applicable
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-
qjospesrru(skrifigkre) = pfhlnptglc gnlfybwfdd (zvhpyndmtd )
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01 Jan 2013
Not Applicable
Maintenance
155
(muerwsjdgx) = oieviopvsy ardtiemokg (mqcpkprwap )
-
01 Jan 2007
(muerwsjdgx) = hxfjnsxsbx ardtiemokg (mqcpkprwap )
Not Applicable
-
katixtxbgi(ysfkwrrxpq) = hzcpxtaqjv jsaypjcztv (uqokucnzkz )
-
01 Jan 2007
Not Applicable
-
96
vmensvotff(ccvghtkngq) = txrmgpvfdu jzvpcxcnkv (qrisrgevmi )
-
01 Jan 2006
vmensvotff(ccvghtkngq) = tuzehmsdya jzvpcxcnkv (qrisrgevmi )
Not Applicable
887
raxjgsvtrr(eixsxxaefp) = Cases of suspected ABC HSR were reported in 52 subjects (5.9%) completing > 6 weeks of therapy. Eight (0.9%) cases were considered mild (Grade 1), 24 (2.7%) were moderate (Grade 2), 18 (2.0%) were severe (Grade 3 or 4) and 2 cases had missing severity data. Twelve cases were hospitalized; no cases were fatal. Median time to onset of ABC HSR was 8 days (range: 0 - 35 days). hxdmcewzra (xyrfxesbxi )
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01 Jan 2005
Not Applicable
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-
guguvhoicc(bewnmoijym) = one subject withdrew due to GI symptoms attributed to APV (prior to RTV switch) wsjstfeyuc (rpuvidbbdv )
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01 Jan 2001
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Regulation

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