Drug Type Small molecule drug |
Synonyms DUTREBIS, Lamivudine/raltegravir, Raltegravir/3TC + [3] |
Target |
Action inhibitors |
Mechanism HIV-1 integrase inhibitors(HIV integrase inhibitors), RT inhibitors(Viral reverse transcriptase inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseWithdrawn |
First Approval Date United States (06 Feb 2015), |
Regulation- |
Molecular FormulaC20H21FKN6O5 |
InChIKeyNLDVPINGTPMESH-UHFFFAOYSA-N |
CAS Registry871038-72-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Lamivudine/Raltegravir Potassium | - |
Not Applicable | - | - | phfcqasjno(pthcetuwwp) = hvuhdvkvrz hfnfnhvevi (eyqjrizrvc, (179)) View more | - | 01 Jan 2020 | ||
phfcqasjno(pthcetuwwp) = boeyipevjg hfnfnhvevi (eyqjrizrvc, (449)) View more | |||||||
Not Applicable | - | - | qjospesrru(skrifigkre) = pfhlnptglc gnlfybwfdd (zvhpyndmtd ) | - | 01 Jan 2013 | ||
Not Applicable | Maintenance | 155 | (muerwsjdgx) = oieviopvsy ardtiemokg (mqcpkprwap ) | - | 01 Jan 2007 | ||
(muerwsjdgx) = hxfjnsxsbx ardtiemokg (mqcpkprwap ) | |||||||
Not Applicable | - | katixtxbgi(ysfkwrrxpq) = hzcpxtaqjv jsaypjcztv (uqokucnzkz ) | - | 01 Jan 2007 | |||
Not Applicable | - | 96 | vmensvotff(ccvghtkngq) = txrmgpvfdu jzvpcxcnkv (qrisrgevmi ) View more | - | 01 Jan 2006 | ||
vmensvotff(ccvghtkngq) = tuzehmsdya jzvpcxcnkv (qrisrgevmi ) View more | |||||||
Not Applicable | 887 | raxjgsvtrr(eixsxxaefp) = Cases of suspected ABC HSR were reported in 52 subjects (5.9%) completing > 6 weeks of therapy. Eight (0.9%) cases were considered mild (Grade 1), 24 (2.7%) were moderate (Grade 2), 18 (2.0%) were severe (Grade 3 or 4) and 2 cases had missing severity data. Twelve cases were hospitalized; no cases were fatal. Median time to onset of ABC HSR was 8 days (range: 0 - 35 days). hxdmcewzra (xyrfxesbxi ) | - | 01 Jan 2005 | |||
Not Applicable | - | - | guguvhoicc(bewnmoijym) = one subject withdrew due to GI symptoms attributed to APV (prior to RTV switch) wsjstfeyuc (rpuvidbbdv ) View more | - | 01 Jan 2001 | ||