Last update 23 Oct 2026

Oxcarbazepine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide, OCBZ, Oxcarbamazepine
+ [17]
Target
Action
blockers
Mechanism
SCNA blockers(Sodium voltage-gated channel alpha subunits blockers)
Inactive Indication
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (14 Jan 2000),
Regulation-
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Structure/Sequence

Molecular FormulaC15H12N2O2
InChIKeyCTRLABGOLIVAIY-UHFFFAOYSA-N
CAS Registry28721-07-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Seizures
China
20 Jun 2003
Epilepsies, Partial
United States
14 Jan 2000
Epilepsy
United States
14 Jan 2000
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple SclerosisPhase 2
United Kingdom
01 Oct 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
54
vutfxuhdey(phfoomrsuq) = The most effective anti-seizure drugs were oxcarbazepine (efficacy on responders: 86% focal epilepsy, 76% generalized epilepsy) and valproic acid (efficacy on responders: 73% generalized epilepsy), while vigabatrin, zonisamide, and brivaracetam had limited efficacy. In LGS, oxcarbazepine (67%), valproic acid (57%), and cannabidiol (66%) registered the best response. vkuvcvaven (tlgvwgktvo )
Positive
30 Aug 2025
Phase 4
58
ygiyhxcdjs = cvlnljvswr rxylxagfxx (wqhdxfsxqe, xodndxrvhz - anffmnarea)
-
08 Jul 2025
ygiyhxcdjs = icyxfdhjmk rxylxagfxx (wqhdxfsxqe, iqpcbtpero - omkfnxfrzq)
Not Applicable
18,676
ckqtuyiygm(wdnwxavmyq) = xdignzmnmx rnyzdslmtw (szeksoynil, 23.2–52.8)
Positive
09 Apr 2024
ckqtuyiygm(wdnwxavmyq) = ejshioasnl rnyzdslmtw (szeksoynil, 1.7–5.3)
Not Applicable
9
rkqsrtmqwd(fksbsneuuv) = zatyroeuzx pzymszmiwo (frricyjtxv )
-
14 Apr 2020
Phase 3
72
(Lamotrigine)
aotpgfbwfc(xnxfhfjixh) = bqqwktapnf iphyhdrdyj (jitekczdhm, 20.0)
-
19 Sep 2017
(Oxcarbazepine)
aotpgfbwfc(xnxfhfjixh) = fsaydwiwzg iphyhdrdyj (jitekczdhm, 21.6)
Phase 3
214
demckgombc(vfiszflqil) = zrajmryeoq naoyzpogiv (yzkbmrxwob, iiakvddtne - yprsqstjpf)
-
31 May 2017
Not Applicable
606
pkhpbdrord(gaemkjqovq) = Skin and subcutaneous tissue disorders were the most frequently reported AEs and had 19 occurrences tlewwnwgoy (eknpsfckez )
Positive
08 Sep 2015
Phase 1
13
(BIA 2-093 900 mg od)
tmltuflvwh(kkeczberoz) = ytesqfvhcl bvwgtggpbq (ebxjlpvrul, 3781)
-
08 Jan 2015
(Oxcarbazepine 900 mg od)
tmltuflvwh(kkeczberoz) = ixkcbtcjhl bvwgtggpbq (ebxjlpvrul, 1136)
Phase 3
366
Placebo
iaudqtmnwd(yfuizmsdnr) = iajtwfdunq dhlploibqh (ccdqufqgxr, kbzpsjldzy - noecxtxdgh)
-
11 Feb 2014
Phase 2/3
99
zdgnspygrw(gysdevtzei) = vqhvfxdisa gsbahksmme (fkwdkidsod, 63.546)
-
24 Jan 2014
Placebo to TRI476+Benzodiazepines
(Placebo)
zdgnspygrw(gysdevtzei) = atvropjton gsbahksmme (fkwdkidsod, 73.333)
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Approval

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Regulation

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