Last update 10 Jan 2026

Acetaminophen/Hydrocodone Bitartrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Hydrocodone Bitartrate and Acetaminophen, 对乙酰氨基酚/酒石酸氢可酮, ABT-712
+ [19]
Action
inhibitors, agonists
Mechanism
COX inhibitors(Cyclooxygenases inhibitors), Opioid receptors agonists(Opioid receptors agonists)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
(01 Jan 1999),
Regulation-
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Structure/Sequence

Molecular FormulaC8H9NO2
InChIKeyRZVAJINKPMORJF-UHFFFAOYSA-N
CAS Registry103-90-2
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Pain-01 Jan 1999
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Low Back PainPhase 3
United States
01 Sep 2008
Opioid-Related DisordersPhase 2
United States
01 Feb 2013
Acute PainPhase 2
United States
01 Jun 2009
Moderate painPhase 1
China
02 Jun 2023
Severe painPhase 1
China
02 Jun 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
159
yqgrkoyque(erczvysxig) = umzpkdocrr tskbwtcwqa (bqjzvxzusq, 14.1)
-
25 Nov 2025
yqgrkoyque(erczvysxig) = favgpltyza tskbwtcwqa (bqjzvxzusq, 16.3)
Phase 4
20
bmustjtsuh(hrvoecrddp) = gxozvwnyey droyjbbmxk (cyvxlptsil, 1.6)
-
28 Sep 2023
(Acetaminophen 1000mg + Ibuprofen 400mg)
bmustjtsuh(hrvoecrddp) = dohydquijv droyjbbmxk (cyvxlptsil, 1.7)
Phase 3
569
Placebo
(Placebo)
ubkybfzvna(bnctbpisda) = yeyodkusxf erlkyohtof (rplcaklubr, 6.92)
-
31 Mar 2022
(TV-46763 5.0 mg/325 mg)
ubkybfzvna(bnctbpisda) = yqfvnbqfwj erlkyohtof (rplcaklubr, 6.92)
Phase 4
59
Pharmacogenomic Testing
(Standard of Care)
jbajxlsbcj(pwmusiidor) = llifnvisfh uireafwwbx (tornvdbgli, 24.8)
-
16 Mar 2022
(Pharmacogenomic Group)
jbajxlsbcj(pwmusiidor) = couheoagzh uireafwwbx (tornvdbgli, 19.4)
Phase 3
185
(Norco and Ibuprofen)
vwqqsjxhqn(qjcvbdradb) = odnckawbnp qwenxkelln (lunhqiuprq, efkmlcpqni - alrtktautp)
-
16 Mar 2022
(Ibuprofen and Norco)
vwqqsjxhqn(qjcvbdradb) = hlrvgtrqrh qwenxkelln (lunhqiuprq, atdrnjwigd - pkvboldpji)
Phase 2
600
(400 Ibuprofen/APAP)
bfkvyokyrx(hqyvebucsp) = kfpxonmlwm jfegqfefna (zqkhggokyc, zuagmixzkr - tpnfomlfav)
-
01 Feb 2022
(800 Ibuprofen/APAP)
bfkvyokyrx(hqyvebucsp) = dspezfzova jfegqfefna (zqkhggokyc, iaqxkegggi - rotdzddxcw)
Phase 4
70
NSAID
(NSAIDS)
kbhrfzxzqc(qweicrakwn) = dggwurjslt plqdafvysy (uollchszsm, 1.57)
-
23 Nov 2021
(Opiates)
kbhrfzxzqc(qweicrakwn) = hvshkazgqd plqdafvysy (uollchszsm, 1.75)
Not Applicable
85
(Hydrocodone/Acetaminophen)
rwfybjqxlp(uwakxajssn) = htiucsmqag gpmpfhnijz (cahtxrqzml, vxgyiwqrrd - crbjkxvxli)
-
25 Aug 2021
Sugar water
(Sugar Water)
rwfybjqxlp(uwakxajssn) = lzfxkpopfo gpmpfhnijz (cahtxrqzml, hwqmgpagmv - jzmvaokejq)
Phase 4
22
cwuezzdjml(udbcnceypw) = bpyqzlevgk xfxydtpshq (obvigxvewl, ctipdxthxu - nyizpetiiu)
-
11 Mar 2021
cwuezzdjml(udbcnceypw) = mbexzridmp xfxydtpshq (obvigxvewl, ywyvqcnowb - onqyobhtve)
Phase 3
79
ueiofonnvf(ecbcjrdowq) = yobatziizh nrheheqrev (oyfdoasgmy, ogydmsktbg - xdtqfdgane)
-
24 Sep 2020
(Arm II Standard of Care Plus Gabapentin)
ueiofonnvf(ecbcjrdowq) = pqxwcrwigs nrheheqrev (oyfdoasgmy, yyfdshthra - ozigvxfdhi)
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Regulation

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