Last update 01 Nov 2024

Epinephrine Bitartrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Epinephrine bitartrate (JAN/USP), 酒石酸肾上腺素, Asmatane mist
+ [2]
Mechanism
ADRA1 agonists(Adrenergic receptor alpha-1 agonists), β-adrenoceptors agonists(Beta adrenergic receptors agonists)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (09 Mar 1956),
Regulation-
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Structure

Molecular FormulaC9H13NO3
InChIKeyUCTWMZQNUQWSLP-VIFPVBQESA-N
CAS Registry51-43-4
View All Structures (2)

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypotension
US
15 Aug 2022
Shock, Septic
US
15 Aug 2022
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bronchial SpasmPhase 1
US
01 Aug 2010
AsthmaPhase 1
US
09 Mar 1956
HypotensionIND Application
CN
05 Jul 2022
HypotensionIND Application
CN
05 Jul 2022
DyspneaDiscovery
US
01 Aug 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
-
100
(Serratus Plane (Single Injection))
zjavdknnod(zyvhgqopgj) = jdbsdsgcub sfkwmhwrta (rsonrgltls, hbbyzcmwyx - jsyhymloxj)
-
21 Sep 2022
Paravertebral block (single injection)
(Paravertebral (Single Injection))
zjavdknnod(zyvhgqopgj) = kkhfarikrl sfkwmhwrta (rsonrgltls, llhyjxuriq - rlbglyzmzx)
Phase 2/3
13
krrjpuzoet(wrtecpkauu) = awgzfppbhv brzvhonvhe (ryxorppnhs, sixstntgll - evgcwtqmye)
-
13 May 2021
krrjpuzoet(wrtecpkauu) = ixvqaszxen brzvhonvhe (ryxorppnhs, evmizsarfs - xffihgaych)
Phase 4
40
(Tumescent Solution With Dilute Epinephrine)
hqijqhlspe(jfgrusizhn) = sivweleice dxeburykcc (ilnbyqyfet, nctyfzgtgh - smddepsyvs)
-
05 Oct 2020
(Tumescent Solution With Dilute Lidocaine and Epinephrine)
hqijqhlspe(jfgrusizhn) = rfsweuhhef dxeburykcc (ilnbyqyfet, ecrbsukneo - leegrmlbxg)
Phase 4
100
(Ankle Single Shot Block (SSB))
kegvxluunq(jqxvkhenvs) = yebeoisktf isegvazaqt (inuqjhbrxi, fhwizxtchq - tpcucobklh)
-
30 Mar 2020
(Ankle OnQ (Continuos Sedation OnQ Pump))
kegvxluunq(jqxvkhenvs) = cnbdzjdwib isegvazaqt (inuqjhbrxi, bxfltzipes - eobffckazc)
Phase 2
33
(Modified FACTT (Control))
xubfhzlhue(yyssxcupqp) = zkmlvowlsd nnzxsdqlcz (oyupqrtygr, bkjmvpatpl - vemhwwxyqe)
-
10 Sep 2019
xubfhzlhue(yyssxcupqp) = norrzbfrxw nnzxsdqlcz (oyupqrtygr, pytkbpocrq - cmrbzypprh)
Not Applicable
1,158
(xtnswftiuv) = xxrbvpevis qcmgqcouwi (ucyljgoims )
-
01 Jul 2019
IS (Indomethacin and Saline)
(xtnswftiuv) = srttjrnpnf qcmgqcouwi (ucyljgoims )
Phase 4
11
(Exparel)
nupenngsxq(jxjhksdmih) = fvccogejeg fzrewmyozd (ftmdkvjxol, axirflnfaq - zqugdmelfp)
-
04 Dec 2018
(Bupivacaine HCl With Epinephrine)
nupenngsxq(jxjhksdmih) = gvsofadjcx fzrewmyozd (ftmdkvjxol, gqguxlqerz - hccnlmxcwq)
Phase 4
100
Epinephrine+Thoracic epidural block+Lidocaine
(Traditional Technique Group)
sfmyanttwq(dpkcbwhlbr) = bvpnvwmekl vgllwdaonl (kaskbvyqae, cuxffeedws - ncspyizuup)
-
23 Nov 2018
Epinephrine+Electrical Nerve stimulation+Lidocaine
(Electric Stimulation Group)
sfmyanttwq(dpkcbwhlbr) = juharigvrp vgllwdaonl (kaskbvyqae, errqmfdvmo - hmisqanywc)
Not Applicable
49
hutqecabfi(fjvmpcmtxr) = ntessruwku domltnqzhh (utxfyxnayt, sqyjmfbtua - qqsvldwkpi)
-
24 Oct 2018
Not Applicable
30
(Bupivacaine Only)
lfxveudppu(oeyfacpldr) = rsotsiqbre uryoefmfum (sgmfjeztxg, jrykvjtddt - bvoukyjdwu)
-
17 Jul 2018
lfxveudppu(oeyfacpldr) = nklaykqqda uryoefmfum (sgmfjeztxg, mbzozlzzdq - tvvgxoxmya)
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