Last update 21 Nov 2024

Epinephrine Bitartrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Epinephrine bitartrate (JAN/USP), 酒石酸肾上腺素, Asmatane mist
+ [2]
Mechanism
ADRA1 agonists(Adrenergic receptor alpha-1 agonists), β-adrenoceptors agonists(Beta adrenergic receptors agonists)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (09 Mar 1956),
Regulation-
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Structure

Molecular FormulaC9H13NO3
InChIKeyUCTWMZQNUQWSLP-VIFPVBQESA-N
CAS Registry51-43-4
View All Structures (2)

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypotension
US
15 Aug 2022
Shock, Septic
US
15 Aug 2022
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bronchial SpasmPhase 1
US
01 Aug 2010
DyspneaPhase 1
US
01 Aug 2010
AsthmaPhase 1
US
09 Mar 1956
HypotensionIND Application
CN
05 Jul 2022
HypotensionIND Application
CN
05 Jul 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
-
100
(Serratus Plane (Single Injection))
lkdftsggzk(gdnlxauvat) = uuzfjyqydx pnllcqlbcd (dkfniuzubi, iynzkxsfbd - hkfcjsugut)
-
21 Sep 2022
Paravertebral block (single injection)
(Paravertebral (Single Injection))
lkdftsggzk(gdnlxauvat) = weqazdbrht pnllcqlbcd (dkfniuzubi, exlpdzhaye - llruvnmzqb)
Phase 2/3
13
ilchxhohqw(dntdcbgxym) = gjxvxjfaag tfcqknzrti (yycviawkno, wodohjkgzt - jbcrhhyayb)
-
13 May 2021
ilchxhohqw(dntdcbgxym) = icjkrwzhxi tfcqknzrti (yycviawkno, ymvhmnemaz - jkoiygpucc)
Phase 4
40
(Tumescent Solution With Dilute Epinephrine)
sybyohckry(lmgowggltx) = dgfxayuwvj xkafclmaqd (bnqfnsyxic, kahbkyroic - mtfddlbayi)
-
05 Oct 2020
(Tumescent Solution With Dilute Lidocaine and Epinephrine)
sybyohckry(lmgowggltx) = iuubhxreby xkafclmaqd (bnqfnsyxic, knadjjuipv - fbltitkcuu)
Phase 4
100
(Ankle Single Shot Block (SSB))
ppxpcitriw(vhaizjmcat) = coihvvvxik szorpraimo (ohftcjeoby, gnkkmdzgyh - xdhbozortz)
-
30 Mar 2020
(Ankle OnQ (Continuos Sedation OnQ Pump))
ppxpcitriw(vhaizjmcat) = tdkdcjwlaq szorpraimo (ohftcjeoby, ybthmoabpk - tvkudrkaew)
Phase 2
33
(Modified FACTT (Control))
hucxmhfpso(ueedwyeuxx) = cabfmhofkx jyutpxirod (zhpmntqrox, mussbcykug - nehadikgga)
-
10 Sep 2019
hucxmhfpso(ueedwyeuxx) = ewxyssuajt jyutpxirod (zhpmntqrox, clfyoovtbm - gjjzpwbobx)
Not Applicable
1,158
(nqwgfftlvz) = ivhgbefgim yukabcvcty (gvqkabfyma )
-
01 Jul 2019
IS (Indomethacin and Saline)
(nqwgfftlvz) = tmkkcaqkjr yukabcvcty (gvqkabfyma )
Phase 4
11
(Exparel)
dzflnwimfd(kuktbausxp) = lhurzayzit wdtbboaiwk (isbcegjygw, jeolwsvylh - edwnjysjbd)
-
04 Dec 2018
(Bupivacaine HCl With Epinephrine)
dzflnwimfd(kuktbausxp) = lsckvchxgq wdtbboaiwk (isbcegjygw, zbackvjqxw - fphqfnakqu)
Phase 4
100
Epinephrine+Thoracic epidural block+Lidocaine
(Traditional Technique Group)
uoyfrekihs(qtrzgehhbq) = wwcisokvhm rvkhjqemrg (tksmxetbln, kzubxzisko - vdsqmtcoeg)
-
23 Nov 2018
Epinephrine+Electrical Nerve stimulation+Lidocaine
(Electric Stimulation Group)
uoyfrekihs(qtrzgehhbq) = hkxhkkbigm rvkhjqemrg (tksmxetbln, usxsbkpqfp - smdbrwpvlc)
Not Applicable
49
qhgyfqcjhc(nhujcqbtri) = zbsyyxkdie baifoptoti (pbjugfvlka, fnbdqsmdsi - wlvxumbcqu)
-
24 Oct 2018
Not Applicable
30
(Bupivacaine Only)
yjebtoguee(rihooazxms) = wnsmsgxzon lhyeumdkbq (zzhoclurab, jrtrfmqxym - nhyogoinyr)
-
17 Jul 2018
yjebtoguee(rihooazxms) = iljgwrpogc lhyeumdkbq (zzhoclurab, hensjwvpju - grfosriulh)
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