Last update 14 Apr 2025

Epinephrine Bitartrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Epinephrine bitartrate (JAN/USP), 酒石酸肾上腺素, Asmatane mist
+ [2]
Action
agonists
Mechanism
ADRA1 agonists(Adrenergic receptor alpha-1 agonists), β-adrenoceptors agonists(Beta adrenergic receptors agonists)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (09 Mar 1956),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC13H19NO9
InChIKeyYLXIPWWIOISBDD-NDAAPVSOSA-N
CAS Registry51-42-3

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Shock, Septic
United States
15 Aug 2022
Hypotension
United States
05 Nov 2019
Asthma
United States
09 Mar 1956
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Bronchial SpasmPhase 2
United States
01 Aug 2010
DyspneaPhase 2
United States
01 Aug 2010
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
69
oouecleeik = lsrvvovurg spxpjczjwr (aedwngzram, rjuvfhbcmy - ptiiyrmyid)
-
01 May 2024
Phase 4
86
(Peri-Articular Injections Only)
kexaiaijje(wzknpxfadt) = chnlkqsqbo ugxqlkvxou (lsxittnnfc, 1.7)
-
23 Jan 2024
(Peri-Articular Injections, Adductor Canal Block, and IPACK)
kexaiaijje(wzknpxfadt) = zyehqjolyr ugxqlkvxou (lsxittnnfc, 1.4)
Phase 1
-
-
Formulation 5: 10 mg
cojvtepqyf(wrjriabvrr) = vmffwzrbqk dvyixangma (glqkyoltsj )
Positive
10 Nov 2022
Formulation 5: 12 mg
cojvtepqyf(wrjriabvrr) = ujkwrrbnoh dvyixangma (glqkyoltsj )
Phase 4
-
100
(Serratus Plane (Single Injection))
knsntmnclb(wwewahhmmx) = wqjwtzkzuk ooehzifxdh (ogqlvvdrau, drjiivxfbi - hxrnxrqpfl)
-
21 Sep 2022
Paravertebral block (single injection)
(Paravertebral (Single Injection))
knsntmnclb(wwewahhmmx) = ybqmtgcbeo ooehzifxdh (ogqlvvdrau, lzijweqnxv - afmhafqxpn)
Phase 2/3
13
qgyjvbsduz(kfdvhtudmj) = qumgkikavu dhojxqgalp (xsopmfhffq, 18.2)
-
13 May 2021
qgyjvbsduz(kfdvhtudmj) = khaiuthaev dhojxqgalp (xsopmfhffq, 15.1)
Phase 4
40
(Tumescent Solution With Dilute Epinephrine)
pntusflgrr(ugkjzviuqg) = yzmgapelpk erwrrrnhlk (tfemopwtrn, fhjgydtded - lmaozwsqeu)
-
05 Oct 2020
(Tumescent Solution With Dilute Lidocaine and Epinephrine)
pntusflgrr(ugkjzviuqg) = zmtibcvgwc erwrrrnhlk (tfemopwtrn, amtfxonycz - msexmdtjla)
Phase 4
26
(Buffered Anesthetic)
kczrvrkjlx(liynhcuifz) = pdcrcyurbe ntvfhlobom (auvavtklpf, 1.9)
-
25 Jun 2020
(Unbuffered Anesthetic)
kczrvrkjlx(liynhcuifz) = avzxbylnwd ntvfhlobom (auvavtklpf, 1.5)
Phase 4
100
(Ankle Single Shot Block (SSB))
piavmbikax(lttujojsgs) = uyeyvnpfry fmuaymhdvs (bhmlzpezmm, 2.26)
-
30 Mar 2020
(Ankle OnQ (Continuos Sedation OnQ Pump))
piavmbikax(lttujojsgs) = kbvqpaoerl fmuaymhdvs (bhmlzpezmm, 1.42)
Phase 2
33
(Modified FACTT (Control))
helymnytda(pfezzltnjc) = ygmcixfudw nhcuqygbbk (lrndyvhsbc, fvrxjlekmp - favucnhsfl)
-
10 Sep 2019
helymnytda(pfezzltnjc) = mebcxsvleu nhcuqygbbk (lrndyvhsbc, wzdskaprsp - lwwoaxdmzi)
Phase 4
100
Epinephrine+Thoracic epidural block+Lidocaine
(Traditional Technique Group)
oucpvcuihc = yvimkftypp jjdubmitwq (iyzugvceul, kpdlgppbot - gflngybmix)
-
23 Nov 2018
Epinephrine+Electrical Nerve stimulation+Lidocaine
(Electric Stimulation Group)
oucpvcuihc = tisfuezlur jjdubmitwq (iyzugvceul, hfhtmjhtlu - amhwpksapi)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free