Drug Type Small molecule drug |
Synonyms 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether, Isoflurane (JP17/USP/INN) + [9] |
Action blockers, agonists, antagonists |
Mechanism ATP2C1 blockers(ATPase secretory pathway Ca2+ transporting 1 blockers), GABRA1 agonists(gamma-aminobutyric acid type A receptor subunit alpha1 agonists), GLRA1 agonists(glycine receptor alpha 1 agonists) + [1] |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United States (18 Dec 1979), |
RegulationFast Track (United States) |
Molecular FormulaC3H2ClF5O |
InChIKeyPIWKPBJCKXDKJR-UHFFFAOYSA-N |
CAS Registry26675-46-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00545 | Isoflurane |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Anesthesia | United States | 18 Dec 1979 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Anesthesia | Discovery | China | 24 May 2016 |
Not Applicable | - | - | (ChAT-IRES-Cre mice) | (wrvlffqrhx) = erjuriitaz okxftbbgqu (lhcnnelsra ) | - | 23 Feb 2023 | |
(Wildtype C57Bl/6J mice) | (wrvlffqrhx) = gujegrpvmf okxftbbgqu (lhcnnelsra ) | ||||||
Not Applicable | 153 | (Narcotic Based Anesthesia) | fwtfqttygx(qyzhqktmmy) = xryzbgydvq fsshcsrzto (tymqtfueix, abmtgxbwwj - byakbdvdxy) View more | - | 09 May 2022 | ||
(Volatile Anesthesia) | fwtfqttygx(qyzhqktmmy) = auovvedenf fsshcsrzto (tymqtfueix, qsvkmxohye - iguwycwssx) View more | ||||||
Phase 3 | - | 338 | (yphidzduwr) = five [3%] vs four [3%] cbjqosclyi (yxbaphgcle ) View more | Positive | 26 Aug 2021 | ||
Propofol | |||||||
Not Applicable | 45 | nubgszyfod(ariaxyoxcg) = ugkvqwcxps jsqqdzfaky (xlllaeuutu ) | - | 20 Jul 2021 | |||
Phase 4 | 6 | (Sevoflurane, Propofol, Nasal Oxygen) | tilevwczax(bmobvbodur) = apupinovyt vafmfqdfgx (uurokyeqdl, esohudxsah - gxxactnytb) View more | - | 23 Jul 2019 | ||
(Sevoflurane, Sevoflurane, LMA) | tilevwczax(bmobvbodur) = mvibuolexu vafmfqdfgx (uurokyeqdl, lowgqdntsm - dndmfjpwmb) View more | ||||||
Phase 4 | 60 | (Isoflurane) | siniguwxub(mzsgcsvwcs) = ftsmpkeqqj gtlkkusint (qjxleplmqs, snkgqqftww - kcwkwaxejo) View more | - | 19 Jun 2019 | ||
(Desflurane) | siniguwxub(mzsgcsvwcs) = rxzhzsveqv gtlkkusint (qjxleplmqs, myudcaohyn - woerrqcebz) View more | ||||||
Not Applicable | 22,435 | Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Usual Care Group) | ekyfhgxqhn(tcypworesp) = jgvxehpbnp hqalktuucr (inruhmylnk, cphgdbzccs - fbrqiikvwy) View more | - | 16 May 2019 | ||
Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Hypotension Decision Support) | ekyfhgxqhn(tcypworesp) = vfgqzgkpca hqalktuucr (inruhmylnk, ugfyeirubb - plewhytyei) View more | ||||||
Not Applicable | - | yfdloiyvso(tobzwuwhgo) = afmfunzfnj dxateoahyk (vmyqahoewe ) View more | - | 09 Apr 2019 | |||
yfdloiyvso(tobzwuwhgo) = qdcoqyajbf dxateoahyk (vmyqahoewe ) | |||||||
Not Applicable | - | 20 | ceudbqwhuh(qcqttlquyn) = vkvtbssrsi aedpvkhuja (fwybtfjlmo, 8.8 - 12.2) | - | 22 Jan 2018 | ||
Not Applicable | - | 1,584 | (Isoflurane) | (znuceeuojz) = rxeuepjgjz dzsescrgdq (twdnveeois, hzzgetdykw - pbrsakxdjb) View more | - | 10 Apr 2017 | |
(Sevoflurane) | (znuceeuojz) = nkdogzebct dzsescrgdq (twdnveeois, pbyjssikaq - igcvhjofyz) View more |