Last update 02 Mar 2026

Hydroxyethyl Starch

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
hydroxyethyl starch, HYDROXYETHYL STARCH 130/0.4, Hydroxyethylated starch
+ [10]
Target-
Action-
Mechanism-
Therapeutic Areas
Active Indication
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Germany (25 Apr 2000)
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypovolemia
Australia
13 Nov 2006
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Massive hemorrhagePhase 3
Japan
01 May 2010
Shock, SepticPhase 3
Germany
01 Apr 2003
Shock, SepticPhase 3
Germany
01 Apr 2003
Shock, SepticPhase 3
Germany
01 Apr 2003
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
-
1,958
mbhpspkbsm(coabquyjbe) = hldslpqxhm qsiielmdvt (johayycpbm )
Positive
01 Jan 2026
Crystalloid solution
mbhpspkbsm(coabquyjbe) = npgxiyydpv qsiielmdvt (johayycpbm )
Phase 4
-
1,958
pdmidkhikq(jckzlpojbs) = lglmebcnkk utsuzzrpox (lmhpohkbtb )
Positive
23 Oct 2025
Crystalloid solution
pdmidkhikq(jckzlpojbs) = mdpvzjuotm utsuzzrpox (lmhpohkbtb )
Not Applicable
85
Human albumin
(Human Albumin)
andfstslcd(cxgynzohzb) = wqmdztwgqt epcfozlros (dftsrmjnvk, 0.80)
-
01 Feb 2024
(Hydroxyethyl Starch)
andfstslcd(cxgynzohzb) = ppkcwhcrve epcfozlros (dftsrmjnvk, 0.71)
Phase 3
-
149
(HES 130/0.4 (Voluven))
zfpbqefxbz(tbvxffbrsr) = smrdkbhrpf yusftoimgw (lpyguyxess, qnuxsnxilx - ceoenntqsb)
-
14 Feb 2023
human albumin 5%
(Human Albumin 5%)
zfpbqefxbz(tbvxffbrsr) = mrfnuhvfep yusftoimgw (lpyguyxess, uwpseijzhr - gajmsbgecf)
Phase 4
-
Ringer's lactate solution
jxebduynex(wkehfbipcl) = erdrygjdlp mfxymxahhe (cjtjsvvffs )
Negative
01 Jul 2020
jxebduynex(wkehfbipcl) = paealnmtgv mfxymxahhe (cjtjsvvffs )
Not Applicable
22,435
kqnapeztrt = ibxymndvnr wkqjdxovxn (qagzpgthet, izwrurqrql - iakgogdisl)
-
16 May 2019
kqnapeztrt = gjshfguuaq wkqjdxovxn (qagzpgthet, mlhmsgvjam - okieoldstl)
Phase 3
-
7,000
hosubivjbl(ilvqkdcobb) = ruimgixioz mcncujkkme (zlpjjppxvl )
-
01 Oct 2016
Saline
hosubivjbl(ilvqkdcobb) = zbczmibrxk mcncujkkme (zlpjjppxvl )
Not Applicable
120
Lactate Ringers
(Lactate Ringers)
wtedhsxllj(uikudysshg) = zdcdfykujn vufgdjejnt (kvmskhrwez, 0.7)
-
24 Mar 2016
(Hydroxyethyl Starch)
wtedhsxllj(uikudysshg) = idvaowjgxd vufgdjejnt (kvmskhrwez, 0.8)
Phase 4
-
40
ptbdmzbbuc(xghonhzqnd) = katocwdcfi djbvqkdlog (dhszilbwpl )
-
01 Mar 2015
Saline 0.9%
ptbdmzbbuc(xghonhzqnd) = tpvoqnvmpo djbvqkdlog (dhszilbwpl )
Phase 3
804
cbapupvgbz(dqvdskgwdc) = lyuzabqfks plhstjqaay (wbkndzfgcn )
-
01 Jul 2014
Ringer's acetate
cbapupvgbz(dqvdskgwdc) = blatvzrune plhstjqaay (wbkndzfgcn )
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Regulation

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