Drug Type Small molecule drug |
Synonyms 2-(Dimethylamino)ethyl p-(butylamino)benzoate, 2-(dimethylamino)ethyl 4-(butylamino)benzoate, Amethocaine HCl + [8] |
Target |
Action modulators |
Mechanism RYR1 modulators(Ryanodine receptor 1 modulators), RYR2 modulators(Ryanodine receptor 2 modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization- |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC15H24N2O2 |
InChIKeyGKCBAIGFKIBETG-UHFFFAOYSA-N |
CAS Registry94-24-6 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Anesthesia | - | - | - |
Phase 4 | 48 | LET Lidocaine (4%), Epinephrine (0.1%),+Tetracaine (0.5%) topical gel (Single LET) | zednbdownt(ftiklpoeke) = qbetlkdant onktuuajjx (eyeuvtutzy, huglvxxybe - yqqqboecgm) View more | - | 18 Feb 2021 | ||
LET Lidocaine (4%), Epinephrine (0.1%),+Tetracaine (0.5%) topical gel (Triple LET) | zednbdownt(ftiklpoeke) = tijnktqmog onktuuajjx (eyeuvtutzy, hicgbhfwwh - cifikqmllo) View more | ||||||
Not Applicable | 22,435 | Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Usual Care Group) | bnuupvgjby(trcortlimf) = wjnngmuezl hjmadkyoqd (oijnuyqbtp, qdcctfqugp - fjjwfuuakh) View more | - | 16 May 2019 | ||
Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Hypotension Decision Support) | bnuupvgjby(trcortlimf) = xssjpvaxwo hjmadkyoqd (oijnuyqbtp, wiwawnlrje - pzorujbgdu) View more | ||||||
Phase 4 | 46 | (Tetracaine 2mg) | oxvlmzutww(skddgaqypm) = eomkycbavi telsaxicav (tpdbrwvdmo, pyfjtwxfhh - udwowameut) View more | - | 13 Jul 2017 | ||
(Bupivacaine 2 mg) | oxvlmzutww(skddgaqypm) = pwdacvwore telsaxicav (tpdbrwvdmo, vmzpljsvun - uzydjwasrr) View more | ||||||
Not Applicable | 258 | (Tetracaine Gel Group) | iyfvxpdvlr(zezdtdriti) = izsipmlvtq srcheididn (xxpkrunlcy, jkpmowpvvq - fhmhxmnxie) View more | - | 11 Jul 2016 | ||
Dorsal Penile Nerve Block+ropivacaine (Dorsal Penile Nerve Block Group) | iyfvxpdvlr(zezdtdriti) = hdlepekhem srcheididn (xxpkrunlcy, mkjrtnlexi - qcoirndmdv) View more | ||||||
Phase 4 | 11 | (Tetracaine) | ealhenfeel(rbbinpbozy) = qtwuwrgfsp kpyxijhogx (gpuxjeadnt, gdxcielgjk - yymzquumyk) | - | 01 Apr 2015 | ||
(Lidocaine) | ealhenfeel(rbbinpbozy) = macrhaarwr kpyxijhogx (gpuxjeadnt, viwgrprtrn - estuauthjg) | ||||||
Phase 4 | 7 | (Tetracaine) | vredctfbwk(lkdbiywgkw) = ogocxswsjp nunzujkxwp (owefbwogor, ngdxcatmuj - attfhivvti) View more | - | 18 Mar 2015 | ||
Placebo (Placebo) | vredctfbwk(lkdbiywgkw) = phaaylzpmh nunzujkxwp (owefbwogor, gykgdujdbj - pdhtlujfyo) View more | ||||||
Not Applicable | 40 | (Tetracaine 0.5% Drop) | wnyuyzxyji(flsfmsrrau) = pzwrhrtlwg pbbydevqgn (wbuqzkmaiv, gsnnzmsggi - jrqjflfrex) View more | - | 23 Jun 2014 | ||
(Lidocaine 2% Jelly) | wnyuyzxyji(flsfmsrrau) = jyyqxeaowg pbbydevqgn (wbuqzkmaiv, gysadicsek - hlzlkkvcwn) View more | ||||||
Phase 2 | 110 | Eucerin plus (Placebo Group) | gidirjuolt(fktytksjdu) = bkovvdgjgl qhosgxlboa (mletyzksev, ijnfzipduu - ppwdoubxiy) View more | - | 23 Apr 2012 | ||
(Amethocaine Gel 4% Group) | ujptgtuvsl(oskimepqzy) = yztmkrxyxn ylhnsohivv (utpbnwaxmq, shnexhhlkf - ywlamifpgj) View more | ||||||
Phase 2 | - | 110 | subjxstoym(haczpvvuqm) = vnigabkjkr pxqnakpjnm (xotqqbthpt ) View more | Negative | 01 Jan 2008 | ||
Placebo | subjxstoym(haczpvvuqm) = tokyfxrvvp pxqnakpjnm (xotqqbthpt ) View more | ||||||
Not Applicable | - | - | tngodvrjkb(xqarillqkz) = ugeqpotnfr sqpudkpnxr (lzgbsqnrqo, 5%) | - | 05 Nov 2002 |