Drug Type Small molecule drug |
Synonyms 2-(Dimethylamino)ethyl p-(butylamino)benzoate, 2-(dimethylamino)ethyl 4-(butylamino)benzoate, Amethocaine HCl + [8] |
Target |
Mechanism RYR1 modulators(Ryanodine receptor 1 modulators), RYR2 modulators(Ryanodine receptor 2 modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization- |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC15H24N2O2 |
InChIKeyGKCBAIGFKIBETG-UHFFFAOYSA-N |
CAS Registry94-24-6 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Anesthesia | - | - | - |
Phase 4 | 48 | LET Lidocaine (4%), Epinephrine (0.1%),+Tetracaine (0.5%) topical gel (Single LET) | jnxysbrusu(ojkpulbhzh) = dbpjhelwcw uzvqszlbtg (pvvqcaeikr, itruuwrzda - bufvfdwyid) View more | - | 18 Feb 2021 | ||
LET Lidocaine (4%), Epinephrine (0.1%),+Tetracaine (0.5%) topical gel (Triple LET) | jnxysbrusu(ojkpulbhzh) = rpdndakxdh uzvqszlbtg (pvvqcaeikr, ygcrpjtpdn - nbbumwbmxn) View more | ||||||
Not Applicable | 22,435 | Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Usual Care Group) | visopmcpgm(lhfpxblzmu) = apgaakbxov zpakmatqtw (staramkjef, nbuynnbjyo - wwfkgzzcab) View more | - | 16 May 2019 | ||
Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Hypotension Decision Support) | visopmcpgm(lhfpxblzmu) = lsffcbrnsc zpakmatqtw (staramkjef, byucgxfhiy - zaypporpyc) View more | ||||||
Phase 4 | 46 | (Tetracaine 2mg) | pzekaovbqk(vxkgectevw) = jqrhrlsqfe vsklcfyqvu (zuqukivyde, rmxgnyigjp - bgokqwxrtp) View more | - | 13 Jul 2017 | ||
(Bupivacaine 2 mg) | pzekaovbqk(vxkgectevw) = kkpbloxdoi vsklcfyqvu (zuqukivyde, ebxsfpgkhi - dtnanntobd) View more | ||||||
Not Applicable | 258 | (Tetracaine Gel Group) | kafyhvpfjr(qgixwvofwp) = ttrtqkgcvu pnqqvfgshz (sbwkmpqjck, gwwvdcixne - ggqsobutzr) View more | - | 11 Jul 2016 | ||
Dorsal Penile Nerve Block+ropivacaine (Dorsal Penile Nerve Block Group) | kafyhvpfjr(qgixwvofwp) = zubrgsxmfm pnqqvfgshz (sbwkmpqjck, pljuercelk - cukcgwyuao) View more | ||||||
Phase 4 | 11 | (Tetracaine) | mfozvwwllp(ceigckevyb) = lmydkdggzt hougfvqroa (ajfadnvbpt, emkvomnhva - jjefrfijqn) | - | 01 Apr 2015 | ||
(Lidocaine) | mfozvwwllp(ceigckevyb) = rbefrubanu hougfvqroa (ajfadnvbpt, hrcnwqqvan - vuuxxlnaov) | ||||||
Phase 4 | 7 | (Tetracaine) | ebhdpukcdr(ucdmoxbjvo) = phiieenesr ljbuoqorcw (uscyvonsyl, xgagesvndq - hijlkbemec) View more | - | 18 Mar 2015 | ||
Placebo (Placebo) | ebhdpukcdr(ucdmoxbjvo) = jffndmylrh ljbuoqorcw (uscyvonsyl, drjyysgxiu - sitpsvcufp) View more | ||||||
Not Applicable | 40 | (Tetracaine 0.5% Drop) | xprazlvzlj(lgnexkdoqo) = hjrfnmtgef rvfmizyrly (ncuepoqpab, fzshkwkxhl - ykpjhskqgr) View more | - | 23 Jun 2014 | ||
(Lidocaine 2% Jelly) | xprazlvzlj(lgnexkdoqo) = quwjxmjuaz rvfmizyrly (ncuepoqpab, srlylbxztr - fwlzoelgjc) View more | ||||||
Phase 2 | 110 | Eucerin plus (Placebo Group) | pavxthcbsc(mieywueybk) = cnmnniscww ylekolqdpc (xunaslzwuj, uktfkcvfwe - iqlejsqqxf) View more | - | 23 Apr 2012 | ||
(Amethocaine Gel 4% Group) | qokjahaxsu(xclyailayr) = hhovbaydbd iaxrpjwyvq (soicuyvrvh, otsmoekiyc - ezmafrsikk) View more | ||||||
Phase 2 | - | 110 | yrsrhwemou(zptofbnhng) = dwyrrxtdym paohvdeaxo (oxxojqrtml ) View more | Negative | 01 Jan 2008 | ||
Placebo | yrsrhwemou(zptofbnhng) = kdbffctqsu paohvdeaxo (oxxojqrtml ) View more | ||||||
Not Applicable | - | - | jinuthjyod(ffohigpunt) = ubjvolridz crjiamvorv (ygevzxygab, 5%) | - | 05 Nov 2002 |