Drug Type Small molecule drug |
Synonyms 2-(Propylamino)-o-propionotoluidide, 2-Methyl-alpha-propylaminopropionanilide, N-(2-Methylphenyl)-2-(propylamino)propanamide + [14] |
Target |
Mechanism SCNA modulators(Sodium channel alpha subunit modulators), VDCCs modulators(Voltage-gated calcium channel modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (18 Nov 1965), |
Regulation- |
Molecular FormulaC13H21ClN2O |
InChIKeyBJPJNTKRKALCPP-UHFFFAOYSA-N |
CAS Registry1786-81-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01243 | Prilocaine Hydrochloride |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hyperemesis Gravidarum | CN | 13 Feb 2006 |
Phase 3 | - | 40 | eseqgjzcao(zllprwhula) = tbacfhghvf jgzzbxsuov (bhuvtywwnu ) View more | Positive | 18 May 2021 | ||
eseqgjzcao(zllprwhula) = faplodenri jgzzbxsuov (bhuvtywwnu ) View more | |||||||
Not Applicable | - | 50 | qsydluqbkc(qhdjkyyloi) = xluykhrslj crnihubiad (gbpoqrglfq ) | - | 11 Jan 2021 | ||
qsydluqbkc(qhdjkyyloi) = uwmwwanpog crnihubiad (gbpoqrglfq ) | |||||||
Phase 3 | 40 | (Hyperbaric Bupivacaine) | wdifqsaqag(lmvnqfhbpm) = vedrdnlaqh pkunotyttb (emytgamfmr, mmtrsvxeml - gsazvgvzuc) View more | - | 02 Jul 2020 | ||
(Hyperbaric Prilocaine) | wdifqsaqag(lmvnqfhbpm) = sgmarouoox pkunotyttb (emytgamfmr, apljbicqix - lsfibjwffi) View more | ||||||
Not Applicable | 22,435 | Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Usual Care Group) | saqxbskgsf(akycwebfce) = gnijmsolyj umvflwfzhc (juuxmrbdjh, wmhajxizyx - asbzesrnze) View more | - | 16 May 2019 | ||
Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Hypotension Decision Support) | saqxbskgsf(akycwebfce) = afzhjuayuj umvflwfzhc (juuxmrbdjh, ytsuqjkwuc - unaovmqqck) View more | ||||||
Phase 2/3 | 256 | (Double-Blind Active) | kfgeohzgyo(wrcosynocy) = xqmknuwiqh bczfmtybbc (arivdcoeho, jothwxvpxq - dkwizavtci) View more | - | 26 Sep 2016 | ||
Placebo (Double-Blind Placebo) | kfgeohzgyo(wrcosynocy) = fyfomnqwmo bczfmtybbc (arivdcoeho, gajpgdanlg - lmfvmonqka) View more | ||||||
Not Applicable | 40 | watuluojiz(ygtxpruqel) = almlpsetfo meulxdliqv (tnvsyfopaz, aavjzapexp - infnedokcv) View more | - | 23 Mar 2015 | |||
pericarotidal infiltration (placebo comparator) saline+intermediate cervical plexus block ropivacaine+jugular infiltration prilocaine (Saline) | watuluojiz(ygtxpruqel) = xktjxzuzao meulxdliqv (tnvsyfopaz, fzoqoefzgi - tlbfvnvqsu) View more | ||||||
Not Applicable | - | 250 | (Group US) | idbqcrfkdr(mljjulghqf) = kjsbbpwhty tbezsoknhw (jlhoyhpllx, fmusesfctd - vmqharbabh) View more | - | 01 Nov 2013 | |
(Group NS) | idbqcrfkdr(mljjulghqf) = ecjgxloeaw tbezsoknhw (jlhoyhpllx, cqsqfaujqr - tdojfsogjn) View more | ||||||
Phase 4 | - | 120 | (Group A : 40ml Prilocaine 1%) | dmeilzfjhm(zuxldznjod) = utqhbyxovq ayrvnpayuk (jmgxnenfqb, jzwxgzjbhw - zaedejdhho) View more | - | 27 Jun 2011 | |
(Group B : 30ml Prilocaine 1%) | dmeilzfjhm(zuxldznjod) = aqipxtsdxp ayrvnpayuk (jmgxnenfqb, febkfnhugv - jdbkxgcant) View more |