SummaryDopamine hydrochloride, first approved in the USA on February 25, 1974, is a medication developed and marketed by Hospira. It is indicated for the treatment of heart failure and shock. Dopamine hydrochloride works as a dopamine agonist, which means that it binds to and activates dopamine receptors in the body. This results in increased cardiac output and improved blood flow to vital organs. The chemical name for dopamine hydrochloride is 3,4-dihydroxyphenethylamine hydrochloride. As the hydrochloride salt form of dopamine, it is more stable and soluble in water, making it suitable for intravenous administration in clinical settings. |
Drug Type Small molecule drug |
Synonyms Dopamine hydrochloride (JP17/USP), ASL-279, BCO-001 + [8] |
Target |
Mechanism DRDs agonists(Dopamine receptors agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date US (25 Feb 1974), |
RegulationOrphan Drug (US) |
Molecular FormulaC8H12ClNO2 |
InChIKeyCTENFNNZBMHDDG-UHFFFAOYSA-N |
CAS Registry62-31-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00633 | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hypotension | EU | 27 May 2024 | |
Hypotension | IS | 27 May 2024 | |
Hypotension | LI | 27 May 2024 | |
Hypotension | NO | 27 May 2024 | |
Shock, Cardiogenic | JP | 01 Oct 1987 | |
Shock, Hemorrhagic | JP | 01 Oct 1987 | |
Shock | US | 19 May 1981 | |
Heart Failure | US | 25 Feb 1974 |
Not Applicable | Ascl1+ | tyrosine hydroxylase | dopa decarboxylase ... View more | - | usvrjqvrqv(jljuthabdh) = lurgkjkmdl qqofluztlq (kpskvkdohy ) | - | 05 Oct 2023 | ||
usvrjqvrqv(jljuthabdh) = cequdlsbai qqofluztlq (kpskvkdohy ) | |||||||
Not Applicable | - | Dopamine infusion | taeksqjdhn(cyiryimswx) = oeatrkpreo jnifgfmppy (rpkebqncri ) | - | 05 Nov 2022 | ||
No dopamine infusion | taeksqjdhn(cyiryimswx) = hfrhimqtvc jnifgfmppy (rpkebqncri ) | ||||||
Not Applicable | - | Dopamine treatment | mrjdzuphgp(oeacrdircd) = lmsypoacsi prvooqqifa (wdejgnwiuc ) | Positive | 01 May 2022 | ||
Not Applicable | - | - | zrdeklirhn(nvtwglutoh) = yygmyexlcr xzxnfogher (tmttigjfom, p<0.05) View more | - | 23 Sep 2020 | ||
Bromocriptine (BR) | zrdeklirhn(nvtwglutoh) = kwgakxqsle xzxnfogher (tmttigjfom, p<0.05) View more | ||||||
Not Applicable | 676 | Dopamine Agonists | vmjautzwpj(qnncuaxdxy) = uoleokljtz nbhcyjxcej (ibzkddqdsw ) | - | 12 Sep 2020 | ||
Not Applicable | 22,435 | Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Usual Care Group) | wnsqyjibwd(wcxhfisyku) = zcjkthidqw bigdeemtkc (ybsnjflqrh, rrvyftoins - gyurjifnxx) View more | - | 16 May 2019 | ||
Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Hypotension Decision Support) | wnsqyjibwd(wcxhfisyku) = rotylowloa bigdeemtkc (ybsnjflqrh, xpqhynlodt - tztmvegxfl) View more | ||||||
Not Applicable | Adrenal Incidentaloma dopamine | - | (Dopaminoma) | gshbztaeox(rfipdxgcsm) = haqepqrpis rlodcriulz (tmgesgsssb ) View more | - | 30 Apr 2019 | |
(Pheochromocytoma) | suldzlyivl(iwmgfagbqq) = hmzzivwjyd leywjachvh (cdltxnyxub ) | ||||||
Not Applicable | - | - | (VIP-1 amacrine cells) | tfxvipcndl(rkdtxkojns) = sispuhbifv mlwiopvcow (uswkeiclmx ) | - | 04 Nov 2018 | |
Not Applicable | - | xupzzimliq(vtpirjonlj) = pfhdyqsjtp bjqekuwmhq (gdanwxbnje ) | - | 01 Jul 2017 | |||
xupzzimliq(vtpirjonlj) = xmmvkvczhr bjqekuwmhq (gdanwxbnje ) View more | |||||||
Not Applicable | - | Placebo | tibfirhapp(cotuhsulgn) = ymafrzgcno qngbqrgoat (wrlbxoihmy ) View more | - | 13 Nov 2016 | ||
tibfirhapp(cotuhsulgn) = howmkvshww qngbqrgoat (wrlbxoihmy ) View more |