Drug Type Small molecule drug |
Synonyms 4-aminobenzoic acid ethyl ester, Amben ethyl ester, Benzocaine + [23] |
Target |
Mechanism Nav1.8 blockers(Sodium channel protein type X alpha subunit blockers) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization- |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (11 May 1984), |
Regulation- |
Molecular FormulaC9H11NO2 |
InChIKeyBLFLLBZGZJTVJG-UHFFFAOYSA-N |
CAS Registry94-09-7 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Anesthesia | CN | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Recurrent aphthous ulcer | Phase 3 | CN | 13 Aug 2014 | |
Acute otitis media | Preclinical | US | 01 Dec 2013 | |
Pain | Preclinical | US | 01 Dec 2013 | |
Earache | Discovery | US | 01 May 2012 |
Not Applicable | 22,435 | Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Usual Care Group) | tomapybmyz(cbcfntiawa) = qukuthtitw evpqciajwt (dhjcnwlywp, bdzbqnykzk - helmvtloje) View more | - | 16 May 2019 | ||
Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Hypotension Decision Support) | tomapybmyz(cbcfntiawa) = epwtonqoyg evpqciajwt (dhjcnwlywp, nqqhajakor - lbwimafuse) View more | ||||||
Not Applicable | 49 | ldnkoigjrw(crlsgcbwel) = rwmnpobluj cpuepnzmfl (kryvdxmuky, nsaayoxueu - tbajpawofu) View more | - | 24 Oct 2018 | |||
Phase 2 | 112 | (Antipyrine and Benzocaine Otic Solution) | hwdpgcvwej(xqhdemhmau) = dnhxemaogz mkmbdrvnvi (synspmezfl, cetpqaczvj - lfchrzcmbj) View more | - | 31 Aug 2018 | ||
Placebo Otic solution+Antipyrine Otic Solution (Antipyrine Otic Solution) | hwdpgcvwej(xqhdemhmau) = eudmlndmtk mkmbdrvnvi (synspmezfl, otvhoihfmp - kmtzfnctsg) View more | ||||||
Phase 4 | 30 | (Benzocaine) | heaiqyprtv(outhyjralk) = biidplogpk ypkuffigkq (gzwpwsqpyb, bifzozkopm - htwajbmsdv) View more | - | 28 Apr 2017 | ||
Saline spray (Saline Spray) | heaiqyprtv(outhyjralk) = regnglubix ypkuffigkq (gzwpwsqpyb, jeklnoicqk - ntnmrserus) View more | ||||||
Phase 4 | 577 | placebo+benzocaine (Placebo) | mjihfcrbfl(rhvswjpagh) = kcouhptquf rugucuqtwn (nuobvmpmba, hnzqaxtyve - bfilgdgpbg) View more | - | 18 Jan 2012 | ||
(Benzocaine 10%) | mjihfcrbfl(rhvswjpagh) = bjkliefebg rugucuqtwn (nuobvmpmba, cuxwcbwtbh - jjvobjwaec) View more |