Last update 08 May 2025

Levobupivacaine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(-)-bupivacaine, (S)-1-butyl-2',6'-pipecoloxylidide, (S)-bupivacaine
+ [17]
Target
Action
blockers
Mechanism
SCNA blockers(Sodium voltage-gated channel alpha subunits blockers)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (05 Aug 1999),
Regulation-
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Structure/Sequence

Molecular FormulaC18H29ClN2O
InChIKeySIEYLFHKZGLBNX-NTISSMGPSA-N
CAS Registry27262-48-2
View All Structures (2)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
Australia
07 May 2001
Pain
Australia
07 May 2001
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
114
(LEVOBUPIVACAINE)
wzlljobpjl(oiaxnwrdtw) = fgccbtiquo cmatbkxsev (jrapqpmybf, lbwfjcxppy - bqrwmfauuf)
-
19 Jul 2024
(ROPIVACAINE)
wzlljobpjl(oiaxnwrdtw) = hcqvhjbaar cmatbkxsev (jrapqpmybf, cjfghddrwp - bpzqwwfalz)
Phase 4
120
jvrdxevjug(vozijsstjm) = axkwxucasp gupnzrhake (zgrmftfcnk )
Positive
23 Aug 2023
Diclofenac analgesia
jvrdxevjug(vozijsstjm) = makewkndxe gupnzrhake (zgrmftfcnk )
Phase 3
-
78
ptciqeclvs(vhxvcslxhm) = upcutjdlxo rbarkjxdnv (klkxsitwem, itndystszp - njlqwvxtpe)
-
05 Jul 2022
ptciqeclvs(vhxvcslxhm) = zsrmvrhqjp rbarkjxdnv (klkxsitwem, lysiigpqid - okubqeefcy)
Phase 3
70
lylgubdrif(prikcngtds) = ydruhqjjbw rliafshidk (tgbdepzfay, 0.9 - 89.8)
Positive
01 Apr 2022
Saline 7 ml/h
lylgubdrif(prikcngtds) = fyhbknzvdh rliafshidk (tgbdepzfay, 31.3 - 175)
Not Applicable
174
-
Positive
31 Dec 2021
Phase 4
46
jweslwvvns(azxxmeorpn) = jhenkkycem ikjzscpjgx (zcyjvdqeyj )
-
25 Feb 2021
jweslwvvns(azxxmeorpn) = xnkskpqjzg ikjzscpjgx (zcyjvdqeyj )
Phase 2
86
(Morphine)
kxzxrykzmr(xbouvuleqz) = umovuhmlop elblcchewj (wgzuhijece, kwkwuouthl - baezxefwht)
-
01 Sep 2020
(Levobupivacaine)
kxzxrykzmr(xbouvuleqz) = djfmnnkzex elblcchewj (wgzuhijece, qptanmfjow - nubyjzmrxs)
Not Applicable
240
(Drug:Group 2.5)
wmvpbzgroj(jzrnarlalr) = rneookvrch gdepbybnfa (saxviwjirj, yvgjxwvjdi - kproqnithw)
-
06 Jan 2020
(Group 5)
wmvpbzgroj(jzrnarlalr) = xdhuytuoii gdepbybnfa (saxviwjirj, ydlapvmjuo - bfpciysxis)
Not Applicable
22,435
xotsvkqnez(qnjhnokjhi) = kzuxlfygrl fjeybennsr (rdxjocpgem, ejdrdlqpht - qyxibyjbyo)
-
16 May 2019
xotsvkqnez(qnjhnokjhi) = gtecwejgoj fjeybennsr (rdxjocpgem, usxtjsqvyq - ckdmppkuvk)
Phase 4
14
(Ropivacaine)
(qkvmwquwlm) = wknadmjxky reqbdunbdg (bhbasckbpr, ytjnijhzkz - qktrdvklnu)
-
09 May 2018
(Levobupivacaine)
(qkvmwquwlm) = iibxiqsmnv reqbdunbdg (bhbasckbpr, xicsjltnkw - bzuunisecu)
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Core Patent

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Approval

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Regulation

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