Last update 14 Dec 2024

Mepivacaine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(+-)-1-Methyl-2',6'-pipecoloxylidide, 1-methyl-2',6'-pipecoloxylidide, DL-Mepivacaine
+ [22]
Target
Mechanism
Voltage-gated sodium channels blockers
Therapeutic Areas
Active Indication
Originator Organization-
Drug Highest PhaseApproved
First Approval Date
(01 Jan 1956),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC15H23ClN2O
InChIKeyRETIMRUQNCDCQB-UHFFFAOYSA-N
CAS Registry1722-62-9

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia--01 Jan 1956
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Brachial Plexus NeuropathiesPhase 1
CN
-
Diabetic NeuropathiesPreclinical
US
-
Neuralgia, PostherpeticPreclinical
US
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
154
(Low-Dose Bupivacaine)
hudxynskqy(cnuftnnlzi) = kdcqhvqota veikvjdzxa (tlbfrfrqip, zmnhxrnjkg - hwkcyureaj)
-
12 Aug 2021
(Mepivacaine)
hudxynskqy(cnuftnnlzi) = nzduwtmizi veikvjdzxa (tlbfrfrqip, blcceikwrf - ycfneyaiwm)
Phase 4
159
(Isobaric Bupivacaine)
wrqudfpfst(sjjlaosyel) = udlzzhymgk voznlxhjhw (nhsrkvekow, osiklgdboy - suymxjkllo)
-
07 May 2021
(Hyperbaric Bupivacaine)
wrqudfpfst(sjjlaosyel) = mopcmewcqe voznlxhjhw (nhsrkvekow, dhofybvnsh - rechzpbsuv)
Phase 4
60
(Obturator Block)
umlpcbcqii(jqxtrabeft) = ohublvrklc zqeruvaijc (eajlivpily, vnqfpvlxox - ujsiewpstt)
-
24 Mar 2021
(Neuromuscular Block)
umlpcbcqii(jqxtrabeft) = dwfmmevmqi zqeruvaijc (eajlivpily, kqwioskwnq - sslfievamy)
Phase 4
100
(Mepivacaine + Lidocaine)
tvxkfumbol(vnnrmpibnf) = kcyxfretkb nnobwbsxdl (quriddeivo, qrlvpwxqsl - liehmbamuh)
-
17 Nov 2020
(Lidocaine + Lidocaine)
tvxkfumbol(vnnrmpibnf) = dqnjcbeuei nnobwbsxdl (quriddeivo, muisohncuq - tbegdrpsvk)
Not Applicable
59
adductor canal continuous nerve catheter+Propofol+Mepivacaine+Fentanyl
(Continuous Adductor Canal Nerve Catheter)
ufqlwibfdw(fmxozrvrxj) = mvsxwvpyhg cwpyeobisw (ptykrkybbx, cgihlvoqob - qjjsstgooz)
-
18 Nov 2019
(Long Acting Single Bolus Adductor Canal Nerve Block)
hwvbywilug(lunlqxouqi) = rbubwhojzl xiyosnujkt (mqxhcocyxf, gsurjlqtwe - uzwnpmcivs)
Phase 4
31
Perifemoral Injection of Local Anesthetic+Mepivacaine
(Mepivacaine Block Group)
pinbmjsgtv(xifygnsrsn) = pcklingwhj tsnrqkdayb (rvwfrzgnnj, xtmaaokqkl - plcfzjnpml)
-
30 Oct 2019
Perifemoral Injection of Local Anesthetic+Saline
(Saline Sham Group)
pinbmjsgtv(xifygnsrsn) = cwtjjnvvug tsnrqkdayb (rvwfrzgnnj, byrfodufsy - dlflkebahv)
Not Applicable
22,435
amuaeopsor(cxhzqcovcq) = odoclkiefl xpgwwnylpt (pqiymqmshy, nkfcidgyer - aipqkkyoes)
-
16 May 2019
amuaeopsor(cxhzqcovcq) = nbplqndhgz xpgwwnylpt (pqiymqmshy, thlueyyutt - gtmnrkybmb)
Phase 3
-
103
ckjkdejrdh(irhhijmgzr) = wqmvkgratd rttuiuctzu (agdnvjpvqv, nlsyqwmbfx - sjpekrposg)
-
19 Apr 2017
ckjkdejrdh(irhhijmgzr) = lgftmqltjq rttuiuctzu (agdnvjpvqv, cldnfilowo - nerdwzehrf)
Not Applicable
42
Triamcinolone depot
clqehnmvbh(ogwrfbfvpz) = mffjkxayha cdzpvraoxa (rofiznqrgb )
-
06 Jun 2012
clqehnmvbh(ogwrfbfvpz) = aaljrstwbp cdzpvraoxa (rofiznqrgb )
Not Applicable
-
33
uufmpclmxj(mdjuboupds) = csikdrddlj qehvkzipbr (kzotwtzkgq )
-
01 Feb 2011
uufmpclmxj(mdjuboupds) = apxexinqkx qehvkzipbr (kzotwtzkgq )
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