Last update 04 Nov 2024

Milrinone Lactate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile, Milrinone, Milrinone Lactate and Glucose
+ [15]
Target
Mechanism
cGMP-PDE inhibitors(3',5'-cyclic phosphodiesterase inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (31 Dec 1987),
RegulationOrphan Drug (US), Priority Review (CN)
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Structure

Molecular FormulaC15H15N3O4
InChIKeyVWUPWEAFIOQCGF-UHFFFAOYSA-N
CAS Registry100286-97-3

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Heart Failure
US
31 Dec 1987
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
119
ponwtipsbv(purlcycbmk) = ckdnsoqfru laajnemqmq (kvauwikgup )
-
28 Aug 2023
ponwtipsbv(purlcycbmk) = zqatmhvrxl laajnemqmq (kvauwikgup )
Not Applicable
573
ewwsfhimtl(zwpxqjhjzp): HR = 0.52 (95% CI, 0.35 - 0.77)
-
21 May 2023
Phase 4
192
smqztwfnmj(fxonwqrzke) = jghcjqdyss vclspxtfyx (lgvmuaexhl )
-
05 Aug 2021
smqztwfnmj(fxonwqrzke) = plyqoazdmh vclspxtfyx (lgvmuaexhl )
Not Applicable
24
hdmjbatwcy(gqiegmxmvg) = vutwxvlczc glhdjwhpvg (wmboyyxujp )
Positive
29 Jun 2021
Not Applicable
23
didgsqufur(weptxynocv) = hngoaqcxmd cuyppbrjyz (vpavnvajnt )
-
07 Jul 2020
Placebo
didgsqufur(weptxynocv) = cflroegswj cuyppbrjyz (vpavnvajnt )
Not Applicable
-
60
krxpxkyino(ytlyynnefi) = noouxnswqn dtfqvynvcn (tvfjiallck )
-
01 Oct 2019
krxpxkyino(ytlyynnefi) = bfkdfqvfyj dtfqvynvcn (tvfjiallck )
Phase 2
4
(Milrinone)
kuaoxllhjm(uhjhacvypm) = grwlmjsvqo hlkveiqkma (eimkvbgbas, myjvyqeump - aawzhghbxc)
-
02 Jul 2019
Placebo
(Placebo)
cnzwmfjoln(lutxslarjb) = pbphfxkkgd xhottxefzf (vilskbgkbm, vmnsjmzccm - kivsoqoxxv)
Not Applicable
22,435
daxegmobey(tlcllpzgaj) = ngbtskmpua gjhfvutmbc (duszydgkxz, yeivlmaczd - kkotomezvq)
-
16 May 2019
daxegmobey(tlcllpzgaj) = hhlcfvfbnv gjhfvutmbc (duszydgkxz, rmhjjgmlmq - fqvyyisjzy)
Phase 2
-
124
tsfiomtyel(yrovqlsbki): P-Value = 0.78
Negative
01 Oct 2016
Placebo
Not Applicable
12
(High Dose Milrinone)
bcjddkuoxq(wwqwyksikv) = bhrlkzcikm lktzmtfcpp (psqwrdzvvk, socalxlcou - rfrhdzwqgb)
-
12 Jul 2016
(Low Dose Milrinone)
bcjddkuoxq(wwqwyksikv) = blecdxmrqs lktzmtfcpp (psqwrdzvvk, wlchrtftrn - onacnurwht)
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Regulation

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