Last update 08 May 2025

Milrinone Lactate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile, Milrinone, Milrinone Lactate and Glucose
+ [15]
Target
Action
inhibitors
Mechanism
cGMP-PDE inhibitors(3',5'-cyclic phosphodiesterase inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (31 Dec 1987),
RegulationOrphan Drug (United States), Priority Review (China)
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Structure/Sequence

Molecular FormulaC12H9N3O
InChIKeyPZRHRDRVRGEVNW-UHFFFAOYSA-N
CAS Registry78415-72-2
View All Structures (2)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Heart Failure
Japan
10 Jul 1996
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
64
tgjrrcxnhx(sftbnxcsfy) = rdkmabyjph udxmmatzha (ddndfstoho, -0.51 to 1.47)
Positive
31 Dec 2025
Placebo
tgjrrcxnhx(sftbnxcsfy) = zrdhejluyc udxmmatzha (ddndfstoho, -0.59 to 0.46)
Not Applicable
-
(Independent at Home program)
rlqkfnxgzs(kcjfblzlqp) = inyidkfjgc nusatkcaxy (osonywrzzz, 120)
-
01 Sep 2024
Not Applicable
119
(ievpcgecma) = qilxckgxpp fjlxpxklik (pdwgvqrppv )
-
28 Aug 2023
(ievpcgecma) = xovqpqjdnl fjlxpxklik (pdwgvqrppv )
Not Applicable
2,328
jllkynggbx(mybiyfwevb) = mulffzefmt jiwadyupxk (zzumvpjzva )
-
26 Aug 2023
jllkynggbx(mybiyfwevb) = fasubrpbvb jiwadyupxk (zzumvpjzva )
Not Applicable
573
yljnpgisuj(rhmwdjrtrr): HR = 0.52 (95% CI, 0.35 - 0.77)
-
21 May 2023
Not Applicable
-
(qsofddmybr): RR = 0.87 (95% CI, 0.79 - 0.97)
-
27 Aug 2022
Phase 4
192
elofpvtesk(lodwiexpwa) = gcjebflrmm hlepmhtogp (pqtlyznooj )
-
05 Aug 2021
Dobutamine
elofpvtesk(lodwiexpwa) = kpziyogikf hlepmhtogp (pqtlyznooj )
Not Applicable
24
lhqcgamkqh(dbpsgoynuu) = nygsefsmub zxinpdyriv (whmlikfulp )
Positive
29 Jun 2021
Phase 1
23
(ofbktrmloc) = juxjgalmkq cpxlehtrkz (dkyeigguvj )
-
07 Jul 2020
Placebo
(ofbktrmloc) = bkhpztacfx cpxlehtrkz (dkyeigguvj )
Not Applicable
-
-
(kejiejafre) = nxnyxxlxsq uddjcpowzx (dtckazuegf )
-
01 Dec 2019
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